Background: In the last decades, there has been an escalating consumption of antibiotics with the number of antibiotic prescriptions increasing worldwide. Since children are more vulnerable to infectious disease than adults, more antibiotics are prescribed for them. Inappropriate use of antibiotics has resulted in a major increase in the development of multi-drug resistant pathogens with great ...

Antibiotics are substances that have a wide range of uses for treating bacterial illnesses. They may be synthetic, naturally occurring, or semi-artificial. The use antibiotics has enabled the treatment infections, saving and enhancing health numerous patients around globe. Antibiotics, however, not working well enough to stop spread […]

In patients with ventilator-associated pneumonia, systemic use of antibiotics is the cornerstone of medical management. Supplemental use of aerosolized antibiotics with intravenous antibiotics in both experimental and clinical studies has been shown to have the following pharmacologic benefits: (1) aerosolized antibiotics reach the infected lung parenchyma without crossing the pulmonary alveola...

UNLABELLED Gaps in public knowledge about antibiotics have led to calls for public education campaigns about antibiotics, including education of school children. OBJECTIVE This study investigates New Zealand primary school teachers' current level of knowledge about antibiotics, to assess whether this is adequate for providing accurate education for children. METHODS Two hundred and sixty-si...

OBJECTIVE To assess different management strategies for acute infective conjunctivitis. DESIGN Open, factorial, randomised controlled trial. SETTING 30 general practices in southern England. PARTICIPANTS 307 adults and children with acute infective conjunctivitis. INTERVENTION One of three antibiotic prescribing strategies-immediate antibiotics (chloramphenicol eye drops; n = 104), no a...

There is a constant need for new antibacterial drugs owing to the inevitable development of resistance that follows the introduction of antibiotics to the clinic. When a new class of antibiotic is introduced, it is effective at first, but will eventually select for survival of the small fraction of bacterial populations that have an intrinsic or acquired resistance mechanism. Pathogens that are...