نتایج جستجو برای: antibody purification

تعداد نتایج: 220433  

Journal: :modares journal of medical sciences: pathobiology 2010
fatemeh rahbarizadeh vahid khoddami vishteh davood ahmadvand

purpose: the antigen binding fragments of camelids heavy chain antibodies are comprised in one single domain (vhh). the crystal structure of an isolated vhh indicated that it is a problate particle of 2.5 nm in diameter and ∼4 nm high, and has been referred to as a nanobody. the very close similarity of these molecules to human vhs illustrates the potential application of these novel products ...

2013
Janet Chenevert Gerard Pruliere Hirokazu Ishii Christian Sardet Takahito Nishikata

Use of antibodies is a cornerstone of biological studies and it is important to identify the recognized protein with certainty. Generally an antibody is considered specific if it labels a single band of the expected size in the tissue of interest, or has a strong affinity for the antigen produced in a heterologous system. The identity of the antibody target protein is rarely confirmed by purifi...

برادران , بهزاد, عبدالعلی زاده, جلال, مجیدی, جعفر, سینه سپهر , کوشان ,

   Background & Aims: Nowadays, by advent of hybridoma technology in monoclonal antibodies production various cell markers could be evaluated in malignant and non-malignant cells. CD20, non-glycosylated phosphoprotein is as an ideal marker in leukemia and B-cell lymphoma diagnosis which is expressed on more than 95% of normal and neoplastic B-cells except for early B-cells and mature plasma. Th...

Background: Cholera as diarrheal illness is one of the most important causes of death and people's disability in different societies. Colonization factor pili (tcpA) and cholera toxin are the most important factors in the pathogenesis of Vibrio Cholera. B subunit of cholera toxin (ctxB) and tcpA have the ability to induce immune responses. The aims of this study was production of CTXB, TCPA, CT...

Journal: :Colloids and Surfaces B: Biointerfaces 2021

• Anion species-triggered antibody separation under optimized constant temperature. species-responsive retention of antibodies by thermo-resopnsive polymer column. Successful therapeutic monoclonal from contaminants. Although the field drugs has grown larger, production still faces several challenges. Effective purification is required, but conventional method for cost intensive and often cause...

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