T he proinflammatory response of macrophages to stimuli, such as lipopolysaccharide (LPS) or IFN , can be blocked by ligands for peroxisome proliferator-activated receptors (PPARs). However, the mechanisms, and even the validity, of this antiinflammatory role for PPARs has recently come under question. The paper by Welch et al. (1) in this issue of PNAS addresses some of these concerns, and sug...

Antiinflammatory Actions of HDL: A New Insight Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2008 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the American Heart Association, 7272 Arteriosclerosis, Thrombosis, and Vascular Biology doi: 10.1161/ATVBAHA.108.173575 2008;28:1890-1891 Arterioscler Thromb Vasc Biol. http://atvb....