نتایج جستجو برای: antimalarial agents
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In Nigeria, it was reported in 2009 that 84 children were killed as a result of toxic chemicals that were laced with teething medications for babies [1]. In 2012, Angolan custom agents busted counterfeiters importing what turned out to be the largest fake medicine imports in history, when containers shipped from China to Luanda were filled with over 1.4 million packets of fake antimalarial drug...
The addition of N-methylimidazole (NMI) to the reaction of homophthalic anhydride with imines such as pyridine-3-carboxaldehyde-N-trifluoroethylimine (9) reduces the amount of elimination byproduct and improves the yield of the formal cycloadduct, tetrahydroisoquinolonic carboxylate 10. Carboxanilides of such compounds are of interest as potential antimalarial agents. A mechanism that rationali...
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