نتایج جستجو برای: antimetabolite agents

تعداد نتایج: 361048  

Journal: :Transplantology 2022

Multiple case series of kidney transplant recipients with COVID-19 have shown increased mortality compared to nontransplant patients. To date, we do not high-level evidence inform immunosuppression minimization strategies in infected recipients. Most centers, however, adopted an early antimetabolite withdrawal addition other interventions. The epidemiological problem concerns also dialysis pati...

Journal: :Applied and environmental microbiology 2016
Lei Wang Jana Hoffmann Hildegard Watzlawick Josef Altenbuchner

We developed a counterselectable deletion system for Thermus thermophilus HB27 based on cytosine deaminase (encoded by codA) from Thermaerobacter marianensis DSM 12885 and the sensitivity of T. thermophilus HB27 to the antimetabolite 5-fluorocytosine (5-FC). The deletion vector comprises the pUC18 origin of replication, a thermostable kanamycin resistance marker functional in T. thermophilus HB...

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