antimicrobial photodynamic therapy apdt

Introduction: Photodynamic therapy is a noninvasive therapeutic method for tumors with a maximum depth of 5 mm. On the other hand, most photosensitizers are also susceptible to ultrasound waves (the basis of sonodynamic therapy). Therefore, it is expected that a combination of the two therapeutic methods will increase effectiveness of photodynamic therapies for lower doses of sensitizer and cur...

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cytotoxicity and phototoxicity of chlorophyll a/hydroxypropyl-γ-cyclodextrin complex on leishmania major promastigotes

Journal: :iranian journal of medical physics 0

azam jafari parizi m.sc. in medical physics, kerman university of medical sciences, kerman, iran. ameneh sazgarnia associate professor of medical physics, medical physics research center, mashhad university of medical sciences, mashhad, iran. pouran layegh assistant professor of dermatology, research center for skin diseases and cutaneous leishmaniasis, mashad university of medical sciences, mashad, iran. omid rajabi associate professor in medicinal chemistry, medicinal chemistry, faculty of pharmacy, mashhad university of medical sciences, mashhad, iran. habibollah esmaily assistant professor, community medicine &public health dept., faculty of health, mashhad university of medical sciences, mashhad, iran.

introduction: cutaneous leishmaniasis (cl) is a widespread disease that is epidemic in iran, too. photodynamic therapy (pdt) is an attractive modality to treat cancer and hyper proliferative diseases based on the use of a photosensitizer in the presence of oxygen and proper wavelength of light. in consideration of lesion location, lack of systemic involvement and inefficiency of current treatme...

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