نتایج جستجو برای: antinociceptive activities

تعداد نتایج: 380840  

Journal: :Life sciences 1998
S Thongpradichote K Matsumoto M Tohda H Takayama N Aimi S Sakai H Watanabe

Mitragynine (MG), a major alkaloidal constituent extracted from the plant Mitragyna speciosa Korth, is known to exert an opioid-like activity. Our previous study showed the involvement of opioid systems in the antinociceptive activity of MG in the tail-pinch and hot-plate tests in mice. In the present study, to clarify the opioid receptor subtypes involved in the antinociceptive action of MG, w...

Journal: :Biological & pharmaceutical bulletin 2003
Seiichi Kobashi Masayuki Takizawa Hajime Kubo Takayasu Yamauchi Kimio Higashiyama

N-Acyloctahydropyrido[3,2,1-ij][1,6]naphthyridines were synthesized as derivatives of matrine-type alkaloids, and the structure-activity relations were examined by the acetic acid-induced abdominal contraction test. The antinociceptive potencies of N-acyloctahydropyrido[3,2,1-ij][1,6]naphthyridines were significantly lower than those of (+)-matrine. The antinociceptive effects of N-benzyloctahy...

Journal: :Asian Pacific journal of tropical biomedicine 2011
Dnyaneshwar J Taur Maruti G Waghmare Rajendra S Bandal Ravindra Y Patil

OBJECTIVE To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves (MRCL). METHODS Antinociceptive activity was evaluated using acetic acid induced writhing test, formalin induced paw licking and tail immersion method in mice at doses of 100, 125 and 150 mg/kg bw. RESULTS The results indicated that MRCL exhibited considerable antinociceptive activity again...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سیستان و بلوچستان - دانشکده ادبیات و علوم انسانی 1392

abstract the first purpose of this study was to investigate the effect of consciousness-raising (c-r) activities on learning grammatical structures (simple present tense in this case) by iranian guidance school efl learners. the second one was to investigate the effect of gender on learning the simple present tense through c-r activities and tasks. finally, this study aimed to investigate the ...

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