A screening of amorphous, heptahydrate, and tetrahydrate forms disodium guanosine 5′-monophosphate is investigated using an antisolvent crystallization process with the aim to selectively produce each solid form. The concentrations solution are monitored by in situ Raman spectroscopy a calibration tool. Particle sizes particle counts measured elapsed time focal beam reflection measurement. Conc...

The study was devised to prepare berberine nanoparticles by anti-solvent precipitation method and were assessed for their hepatoprotective effect in Male Sprague-Dawley rats against carbon tetrachloride. pharmacokinetic parameters of the prepared evaluated rabbits. Histopathological studies blood biochemical analyses carried out evaluate role both forms experimental animals. Substantial improve...