The global demand for safe and healthy food with minimal synthetic preservatives is continuously increasing. Some natural antimicrobials strong antimicrobial activity low toxicity have been considered as alternatives current commercial preservatives. Nonetheless, these are hardly applied directly to products due issues such flavor or bioavailability. Recent advances in microencapsulation techno...

Andrographis paniculata is a herbal drug of Asian traditional medicine largely employed for the treatment of several diseases. Recently, it has been introduced in Europe for the prophylactic and symptomatic treatment of common cold and as an ingredient of dietary supplements. The active principles are diterpenes with andrographolide as the main representative. In the present study, an analytica...

The aims of this study are to increase and explain the mechanism of dissolution enhancement of isradipine using the sonoprecipitation method for stable nanosuspensions. There have been still few of published researches on formulation of isradipine using nanoparticle engineering. Nanosuspension systems were prepared upon various factors including amplitude and the time length of ultrasonication....

the cu doped nio (nio:cu) nanoparticles were synthesized by co-precipitation method using nicl2.6h2o, cucl2.2h2o for ni and cu sources, respectively. sodium hydroxide has been used as a precipitator agent. effect of cu doping agent on the structural and optical properties of nanostructures were characterized by xrd, sem, afm, spectrophotometry, ftir and vsm techniques. xrd revealed that nio:cu ...

Enhanced metabolic productivity of microbial, plant and animal cells in bioreactors can greatly improve the economics of biotechnology processes. Ultrasound is one method of intensifying the performance of live biocatalysts. Ultrasonication is generally associated with damage to cells but evidence is emerging for beneficial effects of controlled sonication on conversions catalyzed by live cells...

We demonstrate that dispersion of single walled carbon nanotubes (SWNTs) by ultrasonication with phospholipid-polyethylene glycol (PL-PEG) fragments it, thus interfering with its ability to block nonspecific uptake by cells. However, unfragmented PL-PEG promoted specific cellular uptake of targeted SWNTs to two distinct classes of receptors expressed by cancer cells. Since fragmentation is a li...

in this study, synthesis of copper nanoparticles and effect of the reaction conditions on the particle size were investigated. the copper nanoparticles were synthesized and stabilized in a narrow temperature range in the presence of polyvinylpyrrolidone under nitrogen atmosphere. reaction temperature and concentration ratio of the reducing agent to the precursor (r/p) as two main conditions i...

The development of Esomeprazole microspheres using enteric coated polymers, such as Eudragit L100, by antisolvent precipitation method has been the focus recent research in order to achieve best drug concentration along with improved stability and bioavailability without any adverse effects an acidic environment. For microsphere, a 32 factorial design was used, polymer amount rpm being variable...

In this study, folic-dextran-camptothecin (Fa-DEX-CPT) tumor-targeted nanoparticles were produced with a supercritical antisolvent (SAS) technique by using dimethyl sulfoxide (DMSO) as a solvent and carbon dioxide as an antisolvent. A factorial design was used to reveal the effect of various process parameters on the mean particle size (MPS) and morphology of the particles formed. Under the opt...