The authors report the case of a 21-month-old boy with an osteolytic lesion in the proximal region of the right humerus. Based on the clinical history and histological findings, the authors suspected osteitis following BCG vaccination. Symptoms remitted after antituberculosis therapy was initiated, and the patient presented radiological improvement. The authors describe this uncommon entity in ...

We present a case of a 33-year-old woman who presented with phlyctenular conjunctivitis while on treatment for spinal intramedullary tuberculosis. She was treated with topical steroids along with continuation of antitubercular therapy, and improved on this treatment.

Multi-drug resistant strains of Mycobacterium tuberculosis (MDR-TB) are present world wide, and in many areas constitute a serious threat to the efficacy of TB control programs. The most effective strategies to limit further spread of MDR-TB are rapid detection of drug resistance followed by prompt and effective therapy. Routine laboratory diagnosis of drug resistance in TB requires a viable, p...

OBJECTIVE To compare the effectiveness of intermittent with daily chemotherapy (both containing rifampicin) in childhood tuberculosis (age 16yrs) in achieving cure significant improvement. DESIGN Systematic Review and Meta-analysis. METHODS MEDLINE and the Cochrane Library were searched for randomized trials of antitubercular regimens containing rifampicin, in children 16 yrs or less with t...

The beginnings of organized treatment for patients with tuberculosis (TB) in Stettin date back to the last decade of the nineteenth century and are traced to the Municipal Hospital in Stettin-Pommerensdorf (Szczecin-Pomorzany). Treatment of patients with TB in Pomerania improved with the opening of the Tuberculosis Hospital in Hohenkrug (Szczecin-Zdunowo). The author presents the history of the...

Finally, Wallace is correct that broader socioeconomic changes can have a determining effect on tuberculosis morbidity. Cases increased dramatically during the Industrial Revolution and then decreased steadily, even before the advent of antituberculosis agents.2 Nevertheless, effective tuberculosis control programs can reduce disease incidence much more quickly than socioeconomic improvement.3 ...

Isoniazid (INH) is a first-line antitubercular drug. We report a case of a patient who developed a pleural effusion 2 months after starting antitubercular treatment for spinal tuberculosis. Isoniazid was found to be the culprit and its discontinuation caused subsidence of the effusion.

Immunotherapy with Bacillus Calmette-Guérin is widely used for treatment and prophylaxis of superficial urothelial cancer. Complications associated with Bacillus Calmette-Guérin treatment are common. The authors describe a case of granulomatous inflammation of the penis associated with intravesical Bacillus Calmette-Guérin therapy, presenting with multiple erythematous and painless nodules loca...

Sixty clinical isolates of M. tuberculosis, 24 susceptible and 36 resistant to conventional primary antituberculous drugs, were tested against four fluoroquinolones (ciprofloxacin, ofloxacin, pefloxacin and norfloxacin). Ofloxacin and ciprofloxacin were found to be the most active, with minimum inhibitory concentration (MIC) of 0.6 mg/l or less to all strains tested. Strains resistant to isonia...