نتایج جستجو برای: antitubercular therapy
تعداد نتایج: 655580 فیلتر نتایج به سال:
A patient with idiopathic pericardial effusion is reported. Patient developed transient constrictive hemodynamics which recovered with continued empirical use of antitubercular drugs and prednisolone.
TOPIC: Chest Infections TYPE: Medical Student/Resident Case Reports INTRODUCTION: Coccidioidomycosis, a fungal infection endemic to the Southwest United States, can take on many appearances chest imaging. A miliary pattern is seen less frequently. In immunocompromised patient, this be quandary for physicians as it may mimic tuberculosis. CASE PRESENTATION: 34-year-old woman with systemic lupus ...
Article history: Received on: 06/04/2015 Revised on: 22/04/2015 Accepted on: 17/05/2015 Available online: 27/06/2015 Effect of culture conditions and critical medium components on antitubercular pigment production from novel Streptomyces sp D25 isolated from Thar desert, Rajasthan was investigated. Antitubercular pigment from Streptomyces sp. D25 was produced by Agar Surface Fermentation (ASF) ...
Alginate-based oral drug delivery system for tuberculosis: pharmacokinetics and therapeutic effects.
Alginate microparticles were developed as oral sustained delivery carriers for antitubercular drugs in order to improve patient compliance. In the present study, pharmacokinetics and therapeutic effects of alginate microparticle encapsulated antitubercular drugs, i.e. isoniazid, rifampicin and pyrazinamide were examined in guinea pigs. Alginate microparticles containing antitubercular drugs wer...
Spectinamides are a novel class of antitubercular agents with the potential to treat drug-resistant tuberculosis infections. Their antitubercular activity is derived from both ribosomal affinity and their ability to overcome intrinsic efflux mediated by the Mycobacterium tuberculosis Rv1258c efflux pump. This study explores the structure-activity relationships through analysis of 50 targeted sp...
BACKGROUND It has been suggested that deterioration of tuberculosis (TB) during appropriate treatment, termed a paradoxical reaction (PR), is more common and severe in HIV positive individuals on highly active antiretroviral therapy (HAART). METHOD A study was undertaken to determine the frequency of PR and its associated features in a population of HIV+TB+ patients and a similar sized group ...
Tuberculosis still remains a leading cause of death in the world. Currently considerable interest in natural products and their derivatives in the area of drug research for multidrug resistant tuberculosis (MDR-TB). The present investigation focused on identification, isolation, characterization of lead constituents and to determine the antitubercular activity of their enriched fractions and is...
Pyridazine plays a significant role in pharmaceuticals particularly in the field of medicinal chemistry. Several 4-substituted-benzylidene-6-substituted-phenyl-dihydro-pyridazin-3(2H)-one derivatives (3a-q) were synthesized and evaluated for their antimicrobial activities with an aim to obtain promising antitubercular agents. In the first step, 6-aryl-tetrahydro-pyridazin-3-ones (2) were prepar...
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