Cough is a common symptom in children and major cause of outpatient visits. As child's cough can anxiety, interfere sleep impact quality life, parents tend to bring the doctor relieve their symptoms. Once commonly used, antitussives are no longer recommended due inefficiency potential for severe side effects.1 The national guidelines have impacted clinical practice, as use racemic adrenaline br...

Consumption of liquid oral medicine by frequently ill children, significantly increases the risk of tooth demineralization. In this study a survey was conducted wherein the pediatricians, pharmacist and medical representatives of Bhopal city were enquired about the most commonly prescribed liquid oral medicines for children. The four categories of medicines reported were: antipyretics/analgesic...

Delineation of neural mechanisms involved in reflex cough is essential for understanding its many physiological and clinical complexities, and the development of more desirable antitussive agents. Brainstem networks that generate and modulate the breathing pattern are also involved in producing the motor patterns during reflex cough. Neurones of the ventrolateral medulla respiratory pattern gen...

Capsaicin, the pungent extract of red peppers, has been used in clinical research for almost three decades. Capsaicin has gained favor as the provocative agent of choice to measure cough reflex sensitivity, as it induces cough in a safe, reproducible, and dose-dependent manner. One of the major uses of capsaicin cough challenge testing has been to evaluate the effect of a pharmacological interv...

We report a case of probable poisoning with codeine phosphate in a 3-month-old infant, which was associated with excessive dosing and concomitant use of antihistamines. Investigation into the patient's drug history identified the recent use of a proprietary cough and cold medicine containing codeine phosphate and dexchlorpheniramine. The prescribing information, available from a popular prescri...

Inhalation cough challenge has become an accepted method of investigating antitussive agents. It is, therefore, important to examine the degree of tachyphylaxis seen with repeated cough challenge. In addition, different types of challenge may reveal important differences in the neuronal pathways involved in the cough reflex. Citric acid, distilled water and capsaicin were examined to determine ...

BACKGROUND World Health Organisation (WHO) estimates that about half of all medicines are inappropriately prescribed, dispensed and sold and about half of all patients fail to take their medicines properly. OBJECTIVE The overall objective of the study was improving use of medicines in the community by creating awareness among different target groups. MATERIALS AND METHODS It was a pre-post ...

Sleep disturbance is a very common finding in patients with persistent cough1. This is especially apparent in infants with common cold or influenza and the continuous crying can lead to considerable distress for the parents. Cough syrups which are easily available as over the counter medications can induce sleep, and many parents turn to this medication when their infant is suffering from persi...