Biofuel produced from biomass pyrolysis is a good example of highly complex mixture. Detailed understanding its composition prerequisite for optimizing transformation processes and further upgrading conditions. The major challenge in the biofuel derived wide range compounds with high diversity polarity abundance that can be present. In this work, comprehensive analysis using mass spectrometry r...

Lipid peroxidation induced etheno-DNA adducts are promutagenic and have been suggested to play a causal role in the development of human cancers. Therefore, human biomonitoring of etheno-DNA adducts in urine has been suggested as a potential marker for oxidative stress-related DNA damage. For quantitative determination, a column-switching LC/APCIMS/MS method was developed for simultaneous analy...

A quantitative LC-APCI-MS/MS method for simultaneous measurement of opiates, cocaine, and metabolites in hair was developed and validated. Cocaine and opiates were extracted from pulverized hair via sonication in methanol at 37 degrees C for 3 h. Samples were cleaned up using solid-phase extraction. LC separation was achieved in 20 min with identification and quantification by selected reaction...

Lipid peroxidation induced etheno-DNA adducts are promutagenic and have been suggested to play a causal role in the development of human cancers. Therefore, human biomonitoring of etheno-DNA adducts in urine has been suggested as a potential marker for oxidative stress-related DNA damage. For quantitative determination, a column-switching LC/APCI-MS/MS method was developed for simultaneous anal...

distributed in southwestern China, is a traditional Tibetan medicine used as a remedy for hepatitis and cholecystitis. Previous phytochemical investigations using this plant have led to the isolation of various poly-oxygenated xanthones, xanthone glycosides, and flavonoid glucosides. In this paper, we report the isolation and structure elucidation of two new iridoid glycosides senburiside III (...

This work is a review on HPTLC contribution to lipid analysis in complex matrices, the period from 2010 now, lapse of time where hyphenation with other techniques, especially Mass Spectrometry, has experienced an important growth. Scanning densitometry (SD)-UV/FL separated lipids, as core detection and centerpiece for hyphenation, its coupling MS using soft ionization techniques (ESI, APCI, MAL...