Children with Down syndrome (DS) experience congenital and functional medical issues that predispose them to obstructive sleep apnea (OSA). Research utilizing stringent age criteria among samples of infants with DS and OSA is limited. This study examines clinical correlates of OSA among infants with DS. A retrospective chart review was conducted of infants ≤6 months of age referred to a DS clin...

Childhood obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of partial or complete upper airway obstruction during sleep. The disease encompasses a continuum from primary snoring (a benign condition without physiological alterations or associated complications) to increased upper airway resistance, obstructive hypoventilation and OSAS. The prevalence of snoring is h...

Background Systemic carnitine deficiency may present with apnea, hypotonia, and poor growth. Premature infants often manifest these symptoms and are at risk of developing carnitine deficiency because of immaturity of the biosynthetic pathway, lack of sufficient predelivery transplacental transport, and lack of sufficient exogenous supplementation. Objective This study was undertaken to examine ...

background: sleep apnea is associated with increased risk ofdiabetes mellitus. however, no studies have compared sleep apneasymptoms in diabetic patients and their first degree relatives.the purpose of our study was to investigate high risk for sleepapnea syndrome, in diabetics and their first degree relatives forprevention of diabetes in family.methods: as a part of a cohort study, all of diab...

BACKGROUND Hypoxic ventilatory depression in mice and muscle fatigue in adult humans are improved by creatine supplementation (CS). Because these issues may be operative in apnea of prematurity (AOP), we hypothesized that CS reduces episodes of hypoxemia and bradycardia in infants with AOP. METHODS Infants were eligible for this double-blind, controlled trial if gestational age was <32 weeks ...

549 IN NEONATES, THE INCIDENCE OF APNEA DEPENDS ON A VARIETY OF FACTORS, SUCH AS BIRTH WEIGHT,1 SEX,2 GESTATIONAL AGE,3 AND POSTNATAL AGE.3,4 Central apnea is generally reported as occurring more frequently during active sleep than during quiet sleep.2,3,5-7 Many authors have pointed out that apnea incidence is also closely related to ambient temperature in both full-term8-10 and preterm neonat...