Arc is a unique immediate early gene (IEG) whose expression is induced as synapses are modified during learning. Newly-synthesized Arc mRNA is rapidly transported throughout dendrites and localizes near recently activated synapses. Arc mRNA levels are regulated by rapid degradation, which is accelerated by synaptic activity in a translation-dependent process. One possible mechanism is nonsense-...

We deal with different algorithmic questions regarding properly arc-colored s-t paths, trails and circuits in arc-colored digraphs. Given an arc-colored digraph D with c ≥ 2 colors, we show that the problem of maximizing the number of arc disjoint properly arc-colored s-t trails can be solved in polynomial time. Surprisingly, we prove that the determination of one properly arc-colored s-t path ...

Although still in its infancy, metal additive manufacturing (AM) or 3D printing has now arrived at a scale suitable for use construction. The new technology offers the potential improved economy, sustainability, safety and productivity through greater automation, enhanced customisation, reduced material usage wastage. In this paper, review of recent developments AM structural engineering is pre...

Arc plasma possesses a constriction phenomenon with a pulsed current. The constriction is created by the Lorentz force, the radial electromagnetic force during arc welding, which determines the energy distribution of the arc plasma. Welding experiments were carried out with ultra-high-frequency pulsed arc welding (UHFP-AW). Ultra-high-speed camera observations were produced for arc surveillance...

This study investigates the dosimetry and radiobiological model variation when a second photon arc was added to prostate volumetric-modulated arc therapy (VMAT) using the single-arc technique. Dosimetry and radiobiological model comparison between the single-arc and double-arc prostate VMAT plans were performed on five patients with prostate volumes ranging from 29-68.1 cm3. The prescription do...

Expression of activity-regulated cytoskeleton associated protein (Arc) is crucial for diverse types of experience-dependent synaptic plasticity and long-term memory in mammals. However, the mechanisms governing Arc-specific translation are little understood. Here, we asked whether Arc translation is regulated by microRNAs. Bioinformatic analysis predicted numerous candidate miRNA binding sites ...