The suprachiasmatic nucleus (SCN) is generally considered the master clock, independently driving all circadian rhythms. We recently demonstrated the SCN receives metabolic and cardiovascular feedback adeptly altering its neuronal activity. In the present study, we show that microcuts effectively removing SCN-arcuate nucleus (ARC) interconnectivity in Wistar rats result in a loss of rhythmicity...

this work is a report 0/9 cases ofarcuate incision for correction 0/astigmatism, after penetrating keratoplasty. plannings were based ojj corneal topography, and the first operation was always arcuate incision alone. 11,e secondary plans were based on refractive errors. the mean of preoperative astigmatism was 6d with the range of5 to 9/). after arcuate incision a/the graft-host interface in th...

OBJECTIVE Glucagon-like peptide-1 (GLP-1) promotes glucose homeostasis through regulation of islet hormone secretion, as well as hepatic and gastric function. Because GLP-1 is also synthesized in the brain, where it regulates food intake, we hypothesized that the central GLP-1 system regulates glucose tolerance as well. RESEARCH DESIGN AND METHODS We used glucose tolerance tests and hyperinsu...

We report the first observation of perinatal death attributable to morphological alterations of the parabrachial/Kölliker-Fuse complex. In an infant, born at 41 weeks of gestation with severe signs of asphyxia and dead 20 h after delivery, we observed the presence of rare and immature neurons in the brain stem areas of both lateral and medial parabrachial nuclei and the absence of the character...