BACKGROUND Results of arterial blood gas analysis can be biased by pre-analytical factors, such as time interval before analysis, temperature during storage and syringe type. OBJECTIVES To investigate the effects of samples storage temperature and time delay on blood gases, bicarbonate and PH results in human arterial blood samples. PATIENTS AND METHODS 2.5 mL arterial blood samples were dr...

Breathing 100% O2 at 1 atmosphere absolute (ATA) is known to be associated with a decrease in cerebral blood flow (CBF). It is also accompanied by a fall in arterial Pco2 leading to uncertainty as to whether the cerebral vasoconstriction is totally or only in part caused by arterial hypocapnia. We tested the hypothesis that the increase in arterial Po2 while O2 was breathed at 1.0 ATA decreases...

BACKGROUND When obtaining an arterial blood sample via percutaneous puncture, there is a risk of accidentally obtaining venous blood. Conventional methods of confirming arterial blood at the bedside, such as blood color and pulsatile return, can be misleading in patients with low blood pressure or hypoxemia. OBJECTIVE To determine if the arterial sampler filling time can be an accurate indic...

Respiratory system modeling has been extensively studied in steady-state conditions to simulate sleep disorders, to predict its behavior under ventilatory diseases or stimuli and to simulate its interaction with mechanical ventilation. Nevertheless, the studies focused on the instantaneous response are limited, which restricts its application in clinical practice. The aim of this study is doubl...

Two previous uncontrolled studies have suggested that noninvasive mechanical ventilation (NIMV) in patients with hypercapnic chronic obstructive pulmonary disease (COPD) improves arterial blood gas tensions by decreasing lung hyperinflation with the consequent reduction in inspiratory loads and changes in ventilatory pattern. The aim of this randomised placebo-controlled study was to determine ...

Natural progesterone, a potent respiratory stimulant, stimulates leptin production in premenopausal females. Leptin and its counterpart neuropeptide Y (NPY) have recently been linked with respiration. The effect of medroxyprogesterone acetate (MPA) on arterial blood gases, serum leptin and NPY was evaluated in this study. Fourteen postmenopausal females with respiratory impairment, due mostly t...

This document provides guidelines for the terminology, methodology, and for the interpretation of data obtained from the use of skin (transcutaneous) po(2) and pco(2) electrodes. The transcutaneous technique has found special application in newborn infants. The causes of analytical bias with respect to arterial blood gas values, and imprecision obtained with transcutaneous pco(2) electrodes, ar...

The objectives in this thesis are to present a model of a variable venturi in an exhaust gas recirculation (EGR) system located in a heavy duty diesel engine. A new legislation called EURO 4 will come into force in 2005 which affects truck development and it will require an On-Board Diagnostic system in the truck. If model based diagnostic systems are to be used, one of the advantages is that t...