OBJECTIVES Prostate cancer tends to spread to regional lymph nodes and bone, and, to a lesser degree, to lung, liver, and brain. Metastases in other locations are exceptional. To review the frequency and clinical characteristics of metastasis to subcutaneous cellular tissue in adenocarcinoma of the prostate. METHODS The case of a 71-year-old man diagnosed of adenocarcinoma of the prostate is ...

3D cultures have gained attention in the field of regenerative medicine for their usefulness as in vitro model of solid tissues. Bottom-up technology to generate artificial tissues or organs is prospective and an attractive approach that will expand as the field of regenerative medicine becomes more translational. We have characterized c-kit positive cardiac stem cells after long-term cultures ...

We propose to develop advanced parallel geometric and numerical algorithms and software for simulating complex flows with dynamic interfaces. The development of scalable, parallel highaccuracy algorithms for simulating such flows poses enormous challenges, particularly on systems with thousands of processors. We will use the resulting tools to simulate blood flow in artificial heart devices. Th...

At the past, damaged tissue was removed from the body of patients. But now tissue regeneration using scaffolds and implants are used to repair the damaged tissue and organs. Besides of the mechanical properties of metallic biomaterials, they suffer from bioinertness. Using some surface treatment techniques, the bioactivity and also corrosion resistance of titanium implants could be improved. In...

A relevant research field is the development of closed-loop combinations of neural tissue and robotics, such as animats and hybrots [4]. As such, a proposed framework for a simple, modular synthetic organism will be evaluated. A closed-loop circulatory system would be used to sustain a “brain” via homeostatic maintenance of a balance of essential nutrients and waste removal. The modular “brains...

Sensory information is acquired in spatial coordinate systems linked to sense organs, yet movement must be executed in coordinate systems linked to motor effector organs. Neurophysiological experiments are yielding new insights into how the brain transforms coordinate systems to facilitate movement.

Previous dynamic characterizations of the cercal mechanosensory hairs of crickets have generally been limited to the first resonant frequency and associated deflection shape. A more complete description of the mechanical dynamics of these structures could be obtained by an experimental modal analysis. This paper describes a method by which a full experimental modal analysis, giving natural freq...

Non-structural carbohydrates (NSC) affect tree growth and survival when photosynthesis is impacted by climate change, such as seasonal drought extreme precipitation. Nevertheless, it still unclear whether Eucalyptus suffers limitation under natural conditions if trees recover artificial cultivation. In present study, we conducted a field control experiment to compare the NSC storage in urophyll...