Based on the reaction of 1,6-diaryl-3, 4-dihydroxy-2, 4-hexadiene-1, 6-dione and arylidene-arylamines various 6-aryl-substituted-4-benzoylacetyl-4-hydroxy-5, 6-dihydro-4H-1, 3-oxazines were synthesized. Due to the relevance of search of new biologically active compounds with antioxidant activity, there was analyzed antiradical activity of derived oxazines. Antiradical properties of these compou...

BACKGROUND Mechano heterocyclic chemistry (MCH) is a recent quickly growing technique in the synthesis of heterocycles and draws the attention of heterocyclic chemists towards the uses of grindstone technique in a solvent free green efficient synthesis of many heterocyclic systems. On the other hand, multicomponent approach has opened the door for the rapid and efficient one-step procedures to ...

We have developed an organophosphane-catalyzed direct β-acylation of a series of conjugated systems bearing ketone, amide and ester functionalities using acyl chlorides as trapping reagents. A wide variety of highly functional ketone derivatives were generated efficiently under very mild conditions with high yields according to our protocol. Our adducts can even be utilized as important buildin...

A new series of Schiff base liquid crystal have been prepared and studied. bases p-alkyl aniline derivatives 4-phenyl pyridine-4?-carbaldehyde were prepared. The terminal alkyl groups substituting are varied chain length, namely C8, C12 C14. structures the compounds elucidated by 1H NMR 13C NMR. mesomorphic thermal optical characteristics samples determined via differential analysis (DSC) polar...

ARTICLE INFO Received: 18/10/2015 Revised: 31/10/2015 Accepted: 11/11/2015 Available Online: 24/11/2015

In the present study, nine bis-azo dyes based on 5-arylidene-2,4-thiazolidinone were obtained in two steps, using Knoevenagel condensation and azo coupling reactions. The structure of the dyes was confirmed on the basis of spectral data. Analysis of spectroscopic data shows that there is equilibrium between the azo and hydrazone tautomers for all dyes in solutions. Investigation of antioxidant ...

Three-component cascade reactions of (E)-3-arylidene-1-methyl-pyrrolidine-2,5-diones, L-valine and various isatin derivatives are described. A series 17 spiropyrrolidine with wide structural complexity diversity have been thus obtained in moderate to excellent yields under mild reaction conditions. The structure stereochemistry these N-heterocyclic cycloadducts has established by spectroscopic ...

Synthesis of 2-[2-(2,6-dichlorophenyl)amino]phenylmethyl-3-[4-(2-substitutedphenyl-4-oxo-thiazolidinyl)aryl]-6-bromo quinazolin-4(3H)ones VIa-j have been achieved from the starting material 2-[(2,6-dichlorophenyl)amino] phenylacetic acid I to benzoxazine III, Further reaction with p-phenylindiamine and substituted aromatic aldehyde gave 2-[2-(2,6-dichlorophenyl)amino]phenyl methyl-3-(4-aminoary...

Synthesis of 2-[2-(2,6-dichlorophenyl)amino]phenylmethyl-3-[4-(2-substitutedphenyl-4-oxo-thiazolidinyl)aryl]-6-bromo quinazolin-4(3H)ones VIa-j have been achieved from the starting material 2-[(2,6-dichlorophenyl)amino] phenylacetic acid I to benzoxazine III, Further reaction with p-phenylindiamine and substituted aromatic aldehyde gave 2-[2-(2,6-dichlorophenyl)amino]phenyl methyl-3-(4-aminoary...