Previous research has shown that numerous age-related changes occur in the subventricular zone (SVZ) and diminish the neurogenic output of the region. Here, various agerelated changes in the structure of the lateral ventricle, the ependymal barrier, and the SVZ were examined. It was found that the walls of the lateral ventricles move together, adhere, and eventually fuse. This results in a degr...

It is a common experience to find in cases with dilated cerebral ventrides that the continuous smooth walls of these cavities give way to irregular contours. The irregularities are composed of transverse rib-like arches which project more deeply into the lumina of the cavities the greater the dilatation. Some patients, however, show large ventricles but may show few and shallow projections into...

The clinical diagnosis of femoral trochlear dysplasia primarily relies on imaging. In the past, plain imaging was the major source of diagnosis. The present study investigated the application of magnetic resonance imaging (MRI) in the objective assessment of severe femoral trochlear dysplasia. A retrospective analysis was performed on knee MRIs from 30 normal subjects (30 knees) and 59 patients...

OBJECTIVES Evidence for an association between duration of untreated illness (DUI) with clinical and functional outcome or brain volume (change) in schizophrenia patients is inconclusive. We aimed to investigate the relationship between DUI, outcome and brain volume at illness onset or brain volume change during the first five years of the illness in first-episode patients. METHODS Magnetic r...

A letter or a three-dimensional shape was presented in the center of the visual field. Following the off-set of this stimulus either a comparison letter or a three-dimensional shape was flashed briefly in either the right or left visual field. The subject's task was to respond SAME, or DIFFERENT. The stimuli could be in the same plane, rotated in two dimensions (letters) or in three dimensions ...