BACKGROUND Pediatric traumatic brain injury (TBI) is an important public health problem and little is known about site of care and outcomes of children with severe TBI. Across the country, most injured children are treated in adult trauma centers (ATCs). Recent literature suggests that ATCs with added qualifications in pediatrics (ATC-AQs) can have improved outcomes for pediatric trauma patient...

BACKGROUND The Korean Society of Thyroid Head and Neck Surgery established a nationwide multicenter registry of anaplastic thyroid carcinoma (ATC) and evaluated the prognostic factors and treatment outcomes of ATC. METHODS The present study enrolled 329 patients who were diagnosed with ATC between January 2000 and December 2012 at 19 medical centers in Korea. Survival outcomes were evaluated ...

Objective: To align pharmacologic classes in ATC and MeSH with lexical and instance-based techniques. Methods: Lexical alignment: we map the names of ATC classes to MeSH through the UMLS, leveraging normalization and additional synonymy. Instance-based alignment: we associate ATC and MeSH classes through the drugs they share, using the Jaccard coefficient to measure class-class similarity. We u...

In order to accurately evaluate the implementation of Area Traffic Control (ATC) system, two situations were compared in this paper, i.e., comparison of intersection performance under two different operation conditions before and after the application of ATC system. Based on floating car theorem, this paper investigated the average intersection delay and the average vehicle stop times. During t...

Abstract Objectives Data on antibiotic consumption in the community were collected from 30 EU/EEA countries over two decades. This article reviews temporal trends, seasonal variation, presence of change-points and changes composition main groups. Methods For period 1997–2017, data antibiotics, i.e. antibacterials for systemic use (ATC group J01), community, aggregated at level active substance,...

Abstract Objectives Data on consumption of tetracyclines, sulphonamides and trimethoprim, other antibacterials were collected from 30 EU/European Economic Area (EEA) countries over two decades. This article reviews temporal trends, seasonal variation, presence change-points changes in the composition main subgroups trimethoprim antibacterials. Methods For period 1997–2017, data tetracyclines (A...

Chemotherapy is one of the most effective forms of cancer treatment and has been used in the treatment of various malignant tumors. We have gained significant insight into the mechanisms of chemoresistance but the details of the molecular mechanisms remain unclear. In the present study, we found that tripartite motif 8 (TRIM8) expression was downregulated in anaplastic thyroid cancer (ATC) tiss...

When the functions of a network element (such as router, switch, etc.) based on Atomic Capability (ATC) architecture are reconstructed dynamically, the topology of ATC will be changed. The process of this reconstruction usually results in the fact that the ATCs being reconfigured cannot process data, and a large parts of the system services suspended and packets discarded. To solve this problem...

The need for estimation of Available transfer Capability (ATC) is very much important in deregulated power system environment as correct estimation of ATC yields economically efficient operation of the restructured power system. This paper presents formulation of a set of AC distribution factors for Static ATC determination and assesses the security of the power system to reliably transfer bulk...

Undifferentiated (anaplastic) thyroid cancer (ATC) is one of the most aggressive human malignancies and no effective therapy is currently available. We show here that PPARγ levels are elevated in cells derived from ATC. Depletion of PPARγ in HTh74 ATC cells resulted in decreased cell growth, cell cycle arrest and a reduction in pRb and cyclin A and B1 levels. We further showed that both flank a...