The methods of analytical target cascading (ATC) and collaborative optimization (CO) are studied with respect to their intended use and applicability. ATC was initially developed as a product development tool, while CO evolved from efforts to coordinate multidisciplinary analyses using a multidisciplinary design optimization (MDO) formulation. ATC and CO are used typically to solve object-based...

generation neural stem cells from neurosphere–derived bone marrow stem cells using bioactive substance atc. bone marrow cells (bmscs) were isolated from rat. bmscs cultured by dmem/f12 medium supplemented with 10% fetal bovine serum. these cells evaluated by specific markers of bmscs such as bioactive substance atc, b27. then bmscs differentionated in to neurosphere and divided in two groups wh...

The USM tower consists of 10 floors used as offices, parking and educational facilities with a total height 48.5 m. Earthquake resistance analysis needs to be carried out on buildings built in earthquake areas. This study uses dynamic the response spectrum method, aiming evaluate structure according SNI 1726:2012. What is reviewed this period, base shear, drift, level building performance. resu...

Background. Anaplastic thyroid cancer (ATC) is one of the tumors with the shortest survival in human medicine. Aim. The aim was to determine the importance of age in survival of patients with ATC. Material and Methods. We analyzed the data on 150 patients diagnosed with ATC in the period from 1995 to 2006. The Kaplan-Meier method and log-rank test were used to determine overall survival. Progno...

Structural MRI (sMRI)-identified tissue "growth" after neuropsychological training has been reported in many studies but the origins of those apparent tissue changes (ATC) still remain elusive. One possible contributor to ATC is brain perfusion since T1-weighted MRI, the tool used to identify ATC, is sensitive to perfusion-change induced tissue T1 alterations. To test the hypothetical perfusion...

Today’s air traffic control (ATC) systems rely on multi-agent collaboration when managing air traffic. The introduction of new technologies into this complex environment motivates a need to assess predictively the impact of future technologies on the work practices currently present within the ATC system. This paper uses principles associated with Clark’s theory of language use (Clark, 1996) to...

OBJECTIVE Anaplastic thyroid cancer (ATC) is one of the most lethal human malignancies. However, the molecular mechanisms of ATC invasion are poorly understood. The transforming growth factor-beta (TGF-β) signaling pathway plays a critical role in promoting tumor metastasis. TGF-β1 was found to be overexpressed in anaplastic thyroid cancer (ATC). We therefore tested our hypothesis that targeted...

We develop a network congestion game to test a series of scenarios in order to analyse potential paths for change in air traffic management in Europe. The two stage game models air traffic control (ATC) providers that set charges and in the second stage airlines that choose flight paths given an airline schedule and the charges from the first stage. The scenarios analysed in the model include (...