The characteristics of train-of-four recovery after atracurium or vecuronium were studied, under enflurane anaesthesia, and compared with those associated with tubocurarine-induced blockade. Ten patients each received vecuronium 0.1 mg kg-1, atracurium 0.5 mg kg-1 or tubocurarine 0.5 mg kg-1. Neuromuscular blockade was calculated as the percent depression of the first twitch, and was determined...

To the Editor: Reddy et al.1 studying neuromuscular-blocking drug (NMBD)induced perioperative anaphylaxis concluded that “the rate of anaphylaxis to succinylcholine and rocuronium is approximately 10-fold higher than to atracurium.” However, we believe that major methodological issues should be highlighted in this article as the authors’ resulting statement might mislead clinical care. First, a...