'(V Tfj aIae T0n tI Kpoias'-Aristotle* ERASISTRATUS AND THE VALVES Erasistratus described all four valves, 'On the Heart' describes only two. Is 'On the Heart' using the discovery which Galen emphatically attributes to Erasistratus, and to no-one else, but using it only in part? This question prompts a further one: what was the real nature of Erasistratus' discovery? References to Erasistratus ...

A 32-year-old man with a 20-year history of palpitation showed a short PQ interval and delta wave on 12-lead ECG. An electrophysiological study showed that the atrio-His (AH) and His-ventricular intervals were not influenced by rapid right atrial pacing or by bolus injection of adenosine triphosphate (ATP). The AH interval was shortened by coronary sinus ostium (CSos) pacing. Ventricular stimul...

To determine the normal function of the Coxsackievirus and Adenovirus Receptor (CAR), a protein found in tight junctions and other intercellular complexes, we constructed a mouse line in which the CAR gene could be disrupted at any chosen time point in a broad spectrum of cell types and tissues. All knockouts examined displayed a dilated intestinal tract and atrophy of the exocrine pancreas wit...

The fluctuating gravitational field in inhomogeneous and clustered self-gravitating systems. Abstract. In this paper I extend the results of Ahmad & Cohen (1973), regarding the study of the probability distribution of the stochastic force in homogeneous gravitational systems, to inhomogeneous gravitational ones. To this aim, I study the stochastic force distribution using N-body realizations of...

As it is known, ischemia of the specialized myocardial excito-conducting tissue is one of the hypothesized mechanisms in atrio-ventricular (A-V) arrhythmias; unfortunately, in the current context of interventional cardiology, which is mainly focused on ablation and/or pacing, the ischemic hypothesis is scarcely taken into consideration. To discuss this hypothesis, which has a solid pathophysiol...

Atrial fibrillation is a common arrhythmia associated with significant morbidity including angina, heart failure and stroke. Medical therapy remains suboptimal with significant side effects and toxicities, as well as a high recurrence rate. Catheter ablation or modification of the atrio-ventricular node with pacemaker implantation provides rate control but subjects the patient to the risks of a...

We report on an atrial tachycardia (AT), emanating from the non-coronary (NC) aortic cusp, ablated with the aid of an electro-anatomical navigation system. In this setting, the electrocardiographic, electrophysiologic (EP), anatomical, and ablative considerations are discussed.Although NC aortic cusp focal ATs are an uncommon EP finding, their ablation is effective and safe, especially from an ...

We encountered a very rare lesion, which included a dissection between a prosthetic patch for repair of an incomplete atrio-ventricular septal defect (AVSD) and a pseudo-intima which had developed. This is the first report of a dissection between an atrial septum patch and pseudo-intima after mitral valve replacement (MVR) in a patient with infective endocarditis following an incomplete AVSD re...