BACKGROUND Supraglottic airway devices (SGA) are commonly used in pediatric anesthesia and serve as primary or back-up devices for difficult airway management. Most SGA are marketed without proper clinical evaluation. The purpose of this study was to evaluate the performance of the pediatric LMA Supreme™, Air-Q® and Ambu® Aura-i™. METHODS This prospective observational study was performed at ...

BACKGROUND Intubating laryngeal mask airways (LMAs) such as i-gel and Aura-i could serve as rescue devices in resuscitation and further ensure the airway by facilitating trachea intubation without ventilation interruption. But data regarding intubating LMAs in novice are limited and skill degeneration without regular training has not been evaluated. So we designed this prospective randomized cr...

BACKGROUND Migraine is common in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) but its treatment responses are not well described, and its relationship to stroke risk unknown. Encephalopathy is a less common presentation; it has been suggested it is related to migraine. We characterised migraine patterns and treatment responses in CADASIL, ...

Background Calcitonin gene-related peptide provokes migraine attacks in 65% of patients with migraine without aura. Whether aggregation of migraine in first-degree relatives (family load) or a high number of risk-conferring single nucleotide polymorphisms contributes to migraine susceptibility to calcitonin gene-related peptide infusion in migraine patients is unknown. We hypothesized that gene...

BACKGROUND Studies have linked migraine with aura to an increased risk of ischemic stroke, particularly among women. Data on the relationship of migraine and functional outcome from ischemic cerebral events are sparse. METHODS AND RESULTS This was a prospective cohort study among 27 852 women enrolled in the Women's Health Study for whom we had information on migraine and measured cholesterol...

The Ozone Monitoring Instrument (OMI) operates onboard NASA’s EOS-AURA satellite, which was launched in July 2004. Aura’s capabilities include Direct Broadcast (DB), i.e. the ability to broadcast data at the same time as they are being measured and stored in the spacecraft’s memory for later transmission to Earth. FMI’s Satellite Data Centre at Sodankylä in Finnish Lapland is exploiting this ca...

This paper discusses an experimental solution that provides the development medium for augmented reality, through a vision based sensory approach. The development medium is a digital toolkit which consists of six modularized components. They are the capture engine (which acquires digital video streams from hardware or media files), the analysis engine (performing various search algorithms), the...

background: migraine is a chronic disease that affects nearly 6% of men and 18% of women worldwide. there are various drugs, which can successfully decrease migraine symptoms and frequency of migraine attacks, but these drugs usually are expensive. hence, this study aimed to assess the effects of pyridoxine  supplementation on severity, frequency and duration of migraine attacks as well as head...

It is often debated whether migraine with aura (MA) and migraine without aura (MO) are etiologically distinct disorders. A previous study using latent class analysis (LCA) in Australian twins showed no evidence for separate subtypes of MO and MA. The aim of the present study was to replicate these results in a population of Dutch twins and their parents, siblings and partners (N = 10,144). Late...

Purified virions of Aura virus, a South American alphavirus related to Sindbis virus, were found to contain two RNA species, one of 12 kb and the other of 4.2 kb. Northern (RNA) blot analysis, primer extension analysis, and limited sequencing showed that the 12-kb RNA was the viral genomic RNA, whereas the 4.2-kb RNA present in virus preparations was identical to the 26S subgenomic RNA present ...