BACKGROUND Autism is a neurodevelopmental disorder with an unclear etiology. Pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) have been suggested to play a role in the etiology of autism. The current study explores the associations among maternal pre-pregnancy BMI, GWG and the risk of autism in the Han Chinese population. METHODS Demographic information, a basic medical h...

More than a hundred de novo single gene mutations and copy-number variants have been implicated in autism, each occurring in a small subset of cases. Mutant mouse models with syntenic mutations offer research tools to gain an understanding of the role of each gene in modulating biological and behavioral phenotypes relevant to autism. Knockout, knockin and transgenic mice incorporating risk gene...

Anecdotal reports and empirical evidence suggest that sensory processing issues are a key feature of autism spectrum conditions. This study set out to investigate whether adults with autism spectrum conditions report more sensory over-responsivity than adults without autism spectrum conditions. Another goal of the study was to identify whether autistic traits in adults with and without autism s...

BACKGROUND Exploring ways to improve the trajectory and symptoms of autism spectrum disorder is prevalent in research, but less is known about the natural prognosis of autism spectrum disorder and course of symptoms. The objective of this study was to examine the temporal stability of autism spectrum disorder and autism diagnosis, and the longitudinal trajectories of autism core symptom severit...

interactome that could be used to develop drugs with potential for treating several different forms of autism. underlie both classic and syndromic autism. It also provides a framework on which to build a much bigger autism protein-protein interaction network provides a starting point for elucidating the common molecular pathways that may gene encoding a protein that turns out to bind to SHANK3....

The U.S. government today announced the latest iteration of Interagency Autism Coordinating Committee, body scientists and advocates that helps set priorities for federally funded autism research services.

OBJECTIVES Reduced pain sensitivity is widely reported to be a common feature of children with autism, yet this conclusion frequently has been based on anecdotal observations and questionable measures of pain. The aims of the study were to (1) characterize the behavioral response of children with autism experiencing a venepuncture using objective observational measures of pain and distress, (2)...

CONTEXT Autism represents an unusual pattern of development beginning in the infant and toddler years. OBJECTIVES To examine the stability of autism spectrum diagnoses made at ages 2 through 9 years and identify features that predicted later diagnosis. DESIGN Prospective study of diagnostic classifications from standardized instruments including a parent interview (Autism Diagnostic Intervi...

Autism is a neurodevelopmental disorder with complex pathophysiology that affects different areas of the brain. Evidence over past decade indicated role for cerebellum in social skills connection neuropathological changes. In this study, we examined cerebellar plasticity rats exhibited autistic-like behaviors after maternal separation (MS). We showed were associated changes volume size. first t...

3. Rimland B, Edelson S. The effect of auditory integration training on autism. Am J of Speech-Language Pathology. 1994;3:16-24. 4. American Academy of Pediatrics. Auditory Integration Training and Facilitated Communication for Autism. Pediatrics. 1998;102(2). 5. Rimland B, Edelson SM. Brief reports: A pilot study of auditory integration training in autism. Journal of Autism and Developmental D...