BackgroundRecommendations for drug withdrawal in patients with autoimmune hepatitis (AIH) longstanding remission are conflicting and rely on retrospective data. We prospectively investigated the predictive value of histological normalisation successful treatment AIH patients.MethodsNon-cirrhotic established complete biochemical (normalisation serum alanine aminotransferase [ALT] or aspartate [A...

Introduction: Acne vulgaris is a chronic inflammatory disease that occurs with various factors, both intrinsic and extrinsic. Treatment of choice can vary from topical, systemic or combination depending on the degree severity. Recently, treatment using products human blood has been widely studied, including in field dermatology as it unique composition.
 Objective: to assess effectiveness ...

AIMS To evaluate the efficacy of 50% autologous serum drops against conventional treatment in ocular surface disorders refractory to normal treatments in a prospective randomised crossover trial. METHOD Patients fulfilling ophthalmological and haematological entry criteria were randomised to either 3 months of autologous serum 50% followed by 3 months of their conventional treatment, or 3 mon...

PURPOSE Acute kidney injury (AKI) in major burn patients is a common complication with high morbidity and mortality. The mainstream treatment is early diagnosis and rapid termination and prevention of the underlying insult. Therefore, it's essential to identify early biomarkers predicting AKI. METHODS A total of 85 patients who were admitted to the burn intensive care unit from June 2012 to J...

AIM To determine the prevalence of Hp infection in patients with chronic urticaria (CU) and to evaluate the result of autologous serum skin test (ASST) in CU patients with Hp infections. METHODS In this cross-sectional study, 16 patients with chronic urticaria and 16 non-urticaria volunteers were investigated (matched for age and sex). All subjects were examined for Hp infection with the 13C-...

The oral adsorbent AST-120 has the potential to delay dialysis initiation and improve survival of patients on dialysis. We evaluated the effect of AST-120 on dialysis initiation and its potential to improve survival in patients with chronic kidney disease. The present retrospective pair-matched study included 560 patients, grouped according to whether or not they received AST-120 before dialysi...

BACKGROUND Autoimmune hepatitis (AIH) is a relapsing inflammatory disease of the liver of unknown cause. Little is known about AIH in Saudi Arabia. OBJECTIVES Our aim is to 1) identify the special clinical or histological features in our patients, 2) describe the initial response to immunosuppressive therapy and long term relapse, 3) identify clinical and laboratory predictors of response to ...

STUDY OBJECTIVE To analyze the impact of a comprehensive care bundle directed by an antimicrobial stewardship team (AST) on the management of candidemia. DESIGN Single-center, quasi-experimental study. SETTING A 930-bed academic hospital. PATIENTS Seventy-eight patients with candidemia were evaluated; 41 patients received the candidemia care bundle (AST group), and 37 did not (historical ...

Introduction: One of the main mechanisms by which diabetic complications occur is an alteration of the structure and function of proteins due to hyperglycemia. Aspirin (ASA) affects cellular pathways through different mechanisms, including glycation inhibition and antioxidant activity. The aim of the present study, as a follow up to our previous one, is to investigate the effect of long-term, h...