BACKGROUND The staging of axillary lymph nodes is critical to the management and prognosis of breast cancer, the most frequent cancer in females. Neoadjuvant therapy and lymph node dissection are recommended when malignant cells invade the lymph nodes. Therefore the pre-operative examination of these lymph nodes is crucial to treatment. METHODS In this study, we examined the effectiveness of ...

PURPOSE Tumor response to neoadjuvant chemotherapy (NAC) may adversely affect the identification and accuracy rate of sentinel lymph node biopsy (SLNB). This study was conducted to evaluate the feasibility of SLNB in node-positive breast cancer patients with negative axillary conversion after NAC. MATERIALS AND METHODS Ninety-six patients with positive nodes at presentation were prospectively...

Invasive micropapillary carcinoma of the breast is of growing clinical significance. The purpose of this study was to identify the radiological imaging features for this type of breast carcinoma and the axillary lymph nodes. The study population consisted of 30 breast cancer patients (8 invasive micropapillary carcinomas and 22 other types of invasive ductal carcinoma). The breast lesions were ...

BACKGROUND The main prognostic factor in early staged breast cancer is the axillary lymph node metastatic affection. Sentinel lymph node biopsy, as a staging modality, significantly decreases surgical morbidity. The status of internal mammary lymph nodes gains an increased predictive role in grading breast carcinomas and modulation of postoperative therapeutic protocols. If positive, almost alw...

The most common cause of metastatic involvement of axillary lymph nodes in women is ipsilateral breast cancer. The definition of occult breast malignancy has changed over time. Nowadays, it is considered to exist when it coincides with an isolated metastatic axillary abnormal lymph node in the absence of a palpable tumor in the ipsilateral breast, non-diagnostic breast tumor mammography and no ...

Metastases to intramammary nodes have been shown to be an independent predictor of poor outcome in patients with breast cancer, such as axillary lymph node metastases. The detection and accurate characterization of these nodes preoperatively is thus crucial for the staging and planning of treatment for breast carcinoma, particularly in cases with axillary lymph node negative disease as it upgra...

Diagnosis In patients aged over 50 years, breast cancer must be differentiated from various forms of senile breast hypertrophy that may be associated with concomitant conditions or, more often, pharmacological treatments that interfere with hormonal metabolism. As in women, careful physical examination of the breast and the regional (axillary and supraclavicular) lymph nodes is essential in men...

We report a case of obstructive jaundice as the initial manifestation of malignant lymphoma. The patient was a 39-year-old woman, who visited our hospital because of epigastralgia and jaundice noted since February 2003. Diagnostic imaging revealed a 40 mm stenosis in the lower bile duct, but biliary biopsy showed no malignancy. FDG-PET revealed accumulation in the left breast, left axillary lym...

Materials and Methods: Electronic medical records of 282 patients (467 breasts) undergoing mastectomy with immediate reconstruction at our institution from 2010–2012 were reviewed to collect clinical and post-operative data. Charts were analysed to determine the association between the absolute number of axillary lymph nodes removed and post reconstructive incidence of skin necrosis, cellulitis...

Metastasis is a multistep process that is not well understood. Colonization of a secondary organ requires specific molecular alterations of the host microenvironment. To determine the temporal and spatial changes associated with metastatic dissemination to the axillary lymph nodes, gene expression profiles were compared between histologically normal lymph nodes from node-positive patients and t...