Fouling and contamination of surfaces are prevailing challenges humanities facing today in fields such as healthcare, hospitality, food manufacturing. These strongly motivate the development multifunctional with antifouling antimicrobial properties that coupled sensing capabilities. To address this challenge, we prepared a superhydrophobic surface using eco-friendly materials: polydimethylsilox...

AIMS To compare the bacteriostatic and bactericidal activity of 13 chemotyped essential oils (EO) on 65 bacteria with varying sensitivity to antibiotics. METHODS AND RESULTS Fifty-five bacterial strains were tested with two methods used for evaluation of antimicrobial activity (CLSI recommendations): the agar dilution method and the time-killing curve method. EO containing aldehydes (Cinnamom...

OBJECTIVE To explore the in vitro antibacterial activity of ethanolic extracts of cinnamon (Cinnamomum zeylanicum; CIN), clove (Syzygium aromaticum, CLV) and cumin (Cuminum cyminum, CMN) against clinical isolates of methicillin resistant Staphylococcus aureus (MRSA), from Kolkata, India. METHODS The CIN, CLV and CMN were tested for their antibacterial activity against MRSA by in vitro methods...

This study was conducted to examine in vitro antibacterialpotential from seed methanol extract of Peganum harmala (L) against some fish pathogenic bacteria including Lactococcus garvieae, Aeromonas hydrophila, Yersinia ruckeri and Pseuodomonas putida isolated from diseased rainbow trout (Oncorhynchus mykiss). The antibacterial activity of extracts was evaluated using disc diffusion assay, m...

To screen large numbers of sera, a method was devised which utilizes the Steers-Foltz replicator which is usually used to determine minimal inhibitory concentration for antibiotics. Each of the wells (9 by 15 mm) of the replicator is filled with 0.06 ml of serum, 0.02 ml of a 10(5) suspension of organisms, and 0.02 ml of diluent (tris(hydroxymethyl)aminomethane-hydrochloride buffer, pH 8.4). Th...

527 percentiles calculated. 2 Applying the BSAC formula 4 to pharmaco-kinetic data (C max of ∼3.2 mg/L following an oral dose of 250 mg with a terminal half-life of 7–8 h), an MIC susceptible breakpoint (BP) of 0.4 mg/L was calculated. MIC data were reviewed to ascertain the ABT-492 MIC ranges for the 'wild sensitive' populations. For Enterobacteriaceae, In the case of staphylococci, the MIC ra...

Early bactericidal activity studies measure the ability of antituberculosis treatments to reduce the burden of Mycobacterium tuberculosis in sputum specimens collected overnight from smear-positive pulmonary tuberculosis patients during the first 14 days of therapy. This confirms the efficacy of novel agents or drug combinations in human patients, allows comparison of different drug dosages and...

The in vitro bactericidal activity of cefazolin was found to be similar to that of cephaloridine and cephalothin but slightly greater than that of cephalexin against a majority of 233 strains of gram-positive and gram-negative organisms. Cefazolin, however, was twoto eightfold more active than the other two drugs against Escherichia coli and klebsiella. The mean peak concentrations in the serum...

The pharmacokinetics of cefuroxime axetil were studied in 10 adult volunteers aged 24 to 31 years (mean age, 27), 22 infants and children aged 11 to 68 months (mean age, 33 months), and 11 children aged 7 years, 7 months to 12 years, 3 months (mean age, 11 years, 1 month). Mean peak plasma concentrations of cefuroxime occurred between 90 and 120 min in all study patients and were independent of...