Type 2 diabetes is characterized by insulin resistance and progressive β-cell deterioration. As β-cell function declines, most patients with type 2 diabetes treated with oral agents, in monotherapy or combination, will require insulin therapy. Addition of basal insulin (glargine, detemir, or NPH/neutral protamine lispro insulin) to previous treatment is accepted as the simplest way to start ins...

Background: In addition to the well-defined histological criteria for squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), immunohistochemical techniques can be used in difficult cases for their differentiation. As differential diagnosis between trichoepithelioma (TE) and BCC is sometimes difficult for the clinician and the pathologist, CD10 may be a useful marker for definite diagnosi...

Background: Radiation-induced basal cell carcinoma (BCC) can be multiple, large, and recurring, which complicates its treatment in some cases. According to reports on the role of cyclooxygenase 2 (COX2) inhibitors in the treatment or prevention of non-melanoma skin cancers and considering the fact that COX2 expression has not been evaluated in radiation-in...

Microdialysis was used to measure the effect of benzodiazepines (BDZs) on basal levels and on stress-induced increases of 5 -hydroxytryptamine (5 -HT), 5 - hydroxyind oleacetic acid (5 -HIAA) , noradrenaline (NA), and dihydroxyphenylacetic acid (DOP AC). The stressors used were a 5 min tail pinch or a 10 min period of restraint. A subcutaneous injection of 5 mg/kg diazepam decreased basal ...

This research was conducted to investigate spatial variability and estimate tree attributes in a plantation forest in the Caspian region of Iran using geostatistical analysis. Sampling was performed based on a 50m?125m systematic grid in a maple stand (Acer velutinum Boiss) 18 years of age using circular samples of 200m2 area. Totally, 96 sample plots were measured in 63 hectares and 14.25 he...

Two independent experiments were conducted with broilers to determine the effect of threonine and vitamin A on immune system. In first experiment, dietary treatments contained 0.8%, 0.87%, 0.94 % and 1.01 % total threonine. In second experiment, diets were as follows: basal diet without vitamin A; basal diet plus 1500 IU/Kg vitamin A; basal diet plus 6250 IU/Kg vitamin A; basal diet plus 11000 ...

The aim of this study was to evaluate the effect of dietary Euphorbia hirta and an acidifier mixture supplementation on gut morphology and some blood parameters of broiler chickens.A total of 240 day old male broiler chicks were randomly assigned to one ofthe four dietary treatment groups including: (1) basal diet (control), (2) basal diet + 7.5 g/kg E. hirta (Eh7.5), (3) basal diet + 1.5 g/kg ...

This study was conducted to examine effects of resistant starch compared to fructooligosaccharide (FOS) and zinc bacitracin (ZnB), on performance and ileum morphology in broilers. The experiment groups included a control (basal diet with no additive; CON), four groups receiving different levels of resistant starch type 2 (1, 2, 3, and 4% added to basal diet; RS), a group receiving fructooligosa...

Background: The mechanisms underlying cerebral hypercapnic vasodilatation are not fully understood. Objective: To investigate the role of nitric oxide (NO) and ATP-sensitive potassium (KATP) channels in basal blood flow regulation and hypercapnia-induced vasodilatation in rabbit cerebral blood vessels. Methods: The change in cerebral blood flow was measured by a laser Doppler flowmeter in 18 Ne...