N Engl J Med 2005;353:2262-9. Copyright © 2005 Massachusetts Medical Society. ccording to the american cancer society, skin cancer is the most common cancer, accounting for about half of all cancers in the United States. More than 1 million cases of skin cancer will be diagnosed in the United States this year. 1 Basal-cell carcinomas constitute approximately 80 percent of all nonmelanoma skin c...

Periungual basal cell carcinoma is rare and needs to be differentiated from other common diseases that affect this region. Several factors are associated with the development of this tumor, and sun damage seems to play an important role in its pathogenesis. Dermoscopy of clinically indolent lesions on the nail unit can shorten the diagnostic process and avoid destructive treatment and functiona...

OBJECTIVE The purpose of this study is to review our series of metastatic basal cell carcinomas of the head and neck. STUDY DESIGN A retrospective review was conducted for this study. METHODS All cases of documented metastatic basal cell carcinomas arising from a primary within the head and neck region and presenting for treatment to one of the authors (Y.D.) were included in this review. ...

Basal Cell Carcinoma (BCC) is the most common malignant tumour of the skin. It is also the most common cancer in humans in some countries. BCC is malignant neoplasm derived from nonkeratinizing cells originating in the basal layer of the epidermis. The histology of the tumour and the surrounding stroma is characteristic. Basal cell carcinoma was first described in 1824 by Jacob who called it "u...

8. Makker R, Ramesh V. On the diagnosis of facial granulomatous dermatoses of obscure origin. International Journal of Dermatology. 2005;44:606-9. 9. Helm KF, Menz J, Gibson LE, Dicken CH. A clinical and histopathologic study of granulomatous rosacea. J Am Acad Dermatol. 1991;25:1038-43. 10. Cribier B, Lieber-Mbomeyo A, Lipsker D. Clinical and histological study of a case of facial Afro-Caribbe...

Skin tumors have become one of the most common cancers in the world and their carcinogenesis is frequently associated with altered glycosylation patterns. The aberrant sialylation, a type of glycosylation, can mediate pathophysiological key events during various stages of tumor progression, including invasion and metastasis. Sialyltransferases play a key role in a variety of biological processe...