Introduction Analytical scientists work closely with research scientists to qualify and support process development. This manuscript demonstrates the importance of coordinating process development R&D with analytical method development from batch through large-scale manufacturing. The initial goal was to demonstrate the capability of Raman spectroscopy for tracking unreacted monomers and comono...

This paper considers a batch gradient method with penalty for training feedforward neural networks. The role of the penalty term is to control the magnitude of the weights and to improve the generalization performance of the network. An usual penalty is considered, which is a term proportional to the norm of the weights. The boundedness of the weights of the network is proved. The boundedness i...

Batch process becomes increasingly important due to greater emphasis on low-volume, higher added value products, and a need for flexibility in market driven environments. The process safety management becomes a crucial issue and its implementation has become a mandatory as the public concern on environmental impacts and safety of chemical industries heightened. This research proposes a risk ana...

In the context of text categorization, Centroid Classifier has proved to be a simple and yet efficient method. However, it often suffers from the inductive bias or model misfit incurred by its assumption. In order to address this issue, we propose a novel batch-updated approach to enhance the performance of Centroid Classifier. The main idea behind this method is to take advantage of training e...

As a rapidly booming industry in recent years, the key problem for Search Engine Marketing (SEM) is to extract web page attributes contributed to the ranking in search engine such as Google and Baidu. The quantitative analysis of these agricultural page attributes is aimed in this paper and the attribute extractor in Java platform is built. Meantime, in order to gain a sample set, a batch gaini...

in this research, a new control policy for the acceptance sampling problem is introduced. decision is made based on the number of defectives items in an inspected batch. the objective of the model is to find a constant control level that minimizes the total costs, including the cost of rejecting the batch, the cost of inspection and the cost of defective items. the optimization is performed by ...

the objective of this work was to develop and evaluate the levofloxacin hemihydrate floating formulations (f1-f9). selection of optimized batch was done by model dependent approach and novel mathematical approach. f1-f9 batches were prepared by direct compression method using gelucire 43/01 (hydrophobic) and hydroxypropylmethylcellulose (hydrophilic) polymer in different ratios. the floating ta...

A public-key cryptosystem is usually used for key management, in particular to session key management. The paper presents a method for handling a batch of concurrent keys with homomorphic publickey cryptosystems such as RSA, Paillier and ElGamal. Theorematically, regardless Shacham and Boneh proved that it is impossible to provide batch RSA encryption of messages with a single certificate, the ...

Hydride generation techniques are used routinely for the determination of As, Se, and Sb in environmental samples. Advantages include high sensitivity, simplicity and relative freedom from interferences. The current method for the hydride generation determination of As and Se, as outlined in the USEPA manual SW-846, utilizes zinc slurry methodology. A batch type method is described. Batch type ...