Alzheimer’s disease is an irreversible neurodegenerative disease, which accounts for most dementia cases. Neuroinflammation increasingly recognised its roles in pathogenesis which, part, links amyloid-beta to neuronal death. Neuroinflammatory signalling can be exhibited by neurons themselves, potentially leading widespread cell death, although neuroinflammation commonly associated with glial ce...

In two experiments, perceptual anticipation--that is, the observer's ability to predict the course of dynamic visual events--in the case of handwriting traces was investigated. Observers were shown the dynamic display of the middle letter l excerpted from two cursive trigrams (lll or lln) handwritten by one individual. The experimental factor was the distribution of the velocity along the trace...

this study was aimed at the evaluation of the influence of storage under various conditions on the relative concentrations of major protein fractions and their proportion in bovine serum. blood samples were taken from six dairy cattle of a low-land black spotted breed and its crossbreeds. the separated blood serum was fractioned into aliquots. one aliquot was analysed immediately after the sepa...

background: type-i diabetes is an autoimmune inflammatory disease in which pancreatic ß-cells are selectively destroyed by infiltrating cells. tnf-related apoptosis-inducing ligand (trail) is a type-ii membrane protein of the tnf superfamily which is expressed in different tissues, including pancreas and lymphocytes. in humans, trail interacts with four membrane receptors. trail-r1 and trail-r2...

The nature of undesirable and unfilterable haze particles observed by craft breweries remains nebulous presents a challenge when the aim is production bright beer. A commercial beer was studied in which brewery had sporadically encountered haze. In this study, it hypothesized that were formed due to increased concentrations proteins, polyphenols, and/or beta-glucans. Samples high low India Pale...

RATIONALE Human heregulins, neuregulin-1 type I polypeptides that activate proliferation, differentiation, and survival of glial cells, neurons, and myocytes, are expressed in macrophage foam cells within human coronary atherosclerotic lesions. Macrophage foam cell formation, characterized by cholesterol ester accumulation, is modulated by scavenger receptor class A (SR-A), acyl-coenzyme A:chol...

the study on the serum protein electrophoresis following thyroidectomy in a puppies showed a significant decrease in the albumin and -a-ratio associated with a relative increase in gamma and total globulin, but alterations of alpha i and beta globulin were not statistically charcteristic in our thyroidectomized dogs.