نتایج جستجو برای: bim based software analysis

تعداد نتایج: 5236333  

2004
CHARLES EASTMAN RAFAEL SACKS GHANG LEE G. LEE

We review the transition now being undertaken from 2D drafting to 3D parametric modeling and the development of Building Information Modeling (BIM). We examine the functionality of BIM platforms, using an example from precast concrete structures. We formulate the development of parametric modeling of building systems from the context of SFB modeling and characterize most parametric modeling as ...

2015
Bohan Tian Kecheng Liu

Building Information Modelling (BIM) seeks to integrate information and business processes throughout the entire building life cycle. This technology is able to generate 3D models that semantically represent facility information dynamically over the life cycle of a building, but is limited when it comes to meeting the needs arising from the operation and management of facility services. There i...

Journal: :Applied sciences 2023

There has been a significant increase in studies related to Industry 4.0 alongside the development of new technologies, devices and software, becoming one most relevant topics for years within so-called Fourth Industrial Revolution (4IR). The Architecture, Engineering Construction sector (AEC) is step behind other engineering fields productivity, digitalisation can help reduce this gap. Buildin...

2018
Andre Vonthron Christian Koch Markus König

Background: The digital process of Building Information Modeling (BIM) involves the creation and modification of CAD-based building models. The complexity of such models has been increasing steadily within the last few years. BIM Models are usually being exchanged using open and standardized data formats. In this context, the Industry Foundation Classes (IFC) are widely used. Therefore, softwar...

2014
Kazutoshi Isobe Yoshinobu Hata Naobumi Tochigi Kyohei Kaburaki Hiroshi Kobayashi Takashi Makino Hajime Otsuka Fumitomo Sato Fumiaki Ishida Naoshi Kikuchi Nao Hirota Keita Sato Go Sano Keishi Sugino Susumu Sakamoto Yujiro Takai Kazutoshi Shibuya Akira Iyoda Sakae Homma

BACKGROUND Germline alterations in the proapoptotic protein Bcl-2-like 11 (BIM) can have a crucial role in tumor response to treatment. To determine the clinical utility of detecting BIM deletion polymorphism in non-small-cell lung cancer positive for epidermal growth factor receptor (EGFR) mutation, we examined outcomes of patients with and without BIM alterations. METHODS We studied 70 pati...

2016
Christoph Merschbrock

Building Information Modeling (BIM) has proven its value for design in the architecture, engineering, and construction industry. However, currently only a few leading firms succeed in reaping the full potential of BIM. Especially, specialist designers remain excluded from innovative practices. Reasons include the technical hurdles of BIM adoption and a misfit between human agency versus the aff...

2017
Faustino Patiño-Cambeiro Guillermo Bastos Julia Armesto Francesco Calise

There is an urgent need for energy efficiency in buildings within the European framework, considering its environmental implications, and Europe’s energy dependence. Furthermore, the need for enhancing and increasing productivity in the building industry turns new technologies and building energy performance simulation environments into extremely interesting solutions towards rigorous analysis ...

2017
Si Sun Hui Yu Huijie Wang Xinmin Zhao Xintai Zhao Xianghua Wu Jie Qiao Jianhua Chang Jialei Wang

BACKGROUND Non-small-cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations might develop primary and secondary resistance to tyrosine kinase inhibitors (TKIs). The proapoptotic protein Bcl-2-like 11 (BIM) is a key modulator of apoptosis triggered by EGFR-TKIs. The recent studies have indicated that some patients with positive EGFR mutations were refractory to ...

Journal: :Blood 2015
Duohui Jing Vivek A Bhadri Dominik Beck Julie A I Thoms Nurul A Yakob Jason W H Wong Kathy Knezevic John E Pimanda Richard B Lock

Glucocorticoids are critical components of combination chemotherapy regimens in pediatric acute lymphoblastic leukemia (ALL). The proapoptotic BIM protein is an important mediator of glucocorticoid-induced apoptosis in normal and malignant lymphocytes, whereas the antiapoptotic BCL2 confers resistance. The signaling pathways regulating BIM and BCL2 expression in glucocorticoid-treated lymphoid ...

2012
Christoph Merschbrock

This paper presents the findings from a study of collaborative work among design professionals in virtual modeling for building construction. The research is based on interviews conducted with members from various design professions. We analyzed a building project comprising a network of organizations interrelated by their information systems, to gain a better understanding of collaborative des...

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