in this study, binding ability of lactobacillus rhamnosus lgg to aflatoxin of pistachio was investigated. results indicate that the bacterium has aflatoxin surface binding ability of 35% (with initial concentration of 10 ppb aflatoxin) in exponential phase. acid and heat treatment increase this ability to 85%. in the second concentration of aflatoxin (20 ppb), this binding ability for viable ce...

In this study at first , an azo dye, 2,7- naphthalenediol, 2-[(4-Bromophenyl)azo (BPAND) as a ligand has been synthesized by addition of p-Bromoaniline to the modified montomorillonite K10 clay. This ligand was characterized using 1H-NMR, UV-Vis and IR spectroscopies. Subsequently, its interaction with calf thymus deoxyribonucleicacid ,ct-DNA was investigated in 5 mM phosphate buffer solution, ...

  Objective(s): A fast and reliable evaluation of the binding energy from a single conformation of a molecular complex is an important practical task. Artificial neural networks (ANNs) are strong tools for predicting nonlinear functions which are used in this paper to predict binding energy. We proposed a structure that obtains binding energy using physicochemical molecular descripti...

In the present study, the binding isotherms for interaction of a homologous series of n-alkyltrimethyl ammonium bromides with bovine serum albumin (BSA) have been analyzed on basis of intrinsic thermodynamic quantities. In this regards, the intrinsic Gibbs free energy of binding, AGb(i,)„ has been estimated at various surfactant concentrations and its trend of variation for both binding sets ha...

The interaction of brilliant green with herring sperm DNA was investigated in detail by spectrometric methods in γ-cyclodextrin systems. On the condition of physiological pH, brilliant green prefers to form the 1:1 inclusion complex with γ-cyclodextrin.All the evidences indicated that the binding modes between γ-cyclode...

Finasteride, a 5-alpha reductase (5α-R) inhibitor, is widely used drug for treating androgen-dependent conditions. However, its use associated with sexual, psychological, and physical complaints, suggesting that other mechanisms, in addition to 5α-R inhibition, may be involved. Here, multidisciplinary approach has been identify potential finasteride off-target proteins. SPILLO-PBSS software sug...

indium is a heavy metal belonging to group iiia. it is used as a radioimaging and chemotherapeutic agent in diagnosis and also in the treatment of cancers. it is believed that indium may interfere with iron metabolism and reduce cell growth in cancer tissue. the present report was established to study the binding of iron and indium to apo-transferrin (apo-tf) and to identify amino acids involve...

in this article, theoretical studies on the selective complexation of the halide ions (f¯, cl¯ and br¯) and ion pairs (na+f¯, na+cl¯ and na+br¯) with the cyclic nano-hexapeptide (cp) composed of l-proline have been performed in the gas phase. in order to calculate the dispersion interaction energies of the cp and ions, dft-d3 calculations at the m05-2x-d3/6-31g(d) level was employed. based on t...