Ever since the advent of bioinformatics to assist research in the research area of protein database query, there are many tools that enabled biologist to query biological databases to elucidate protein secondary structure assignment. However, currently there is a limited means that provides a query capability to search information on secondary structure from structural database in context of pr...

Research in bioinformatics in the past decade has generated a large volume of textual biological data stored in databases such as MEDLINE. It takes a copious amount of effort and time, even for expert users, to manually extract useful information embedded in such a large volume of retrieved data and automated intelligent text analysis tools are increasingly becoming essential. In this article, ...

This paper describes a data mining environment for knowledge discovery in bioinformatics applications. The system has a generic kernel that implements the mining functions to be applied to input primary databases, with a warehouse architecture, of biomedical information. Both supervised and unsupervised classification can be implemented within the kernel and applied to data extracted from the p...

SUMMARY The EMBL Nucleotide Sequence Database, maintained at the European Bioinformatics institute, is Europe's primary nucleotide sequences database. Its entries are subject to changes, but only the most recent versions are preserved in the database. The EMBL Sequence Version Archive is a new publicly available database retaining also the earlier versions of these entries. AVAILABILITY http:...

Bio-oils obtained from southern yellow pine biomass two thermochemical conversion processes, fast pyrolysis (FP) and hydrothermal liquefaction (HTL), were investigated. The effects of FP HTL on the physical chemical properties bio-oils characterized. bio-oil yields 67 36 wt%, respectively. results indicated that similar; however, there variations in composition same biomass. pH values 2.3 2.8, ...

The nature of biological data The life sciences literature presents biological results based on carefully collected, analyzed, and vetted data that researchers can use with high confidence. Everyday bioinformatics, however, deals with raw data collected from recently completed experiments in the form of images, charts, or numbers and with sequence data collected from a wide variety of online da...

The four most important data-related considerations for the bioinformatic analysis of biological systems are understanding of: the complexity and hierarchical nature of processes that generate biological data, fuzziness of biological data, biases and potential misconceptions in data, and the effects of noise and errors. We discuss these issues and summarize our findings by defining a Data Learn...

Bioinformaticians seeking to provide services to working biologists are faced with the twin problems of distribution and diversity of resources. Bioinformatics databases are distributed around the world and exist in many kinds of storage forms, platforms, and access paradigms. To provide adequate services to biologists, these distributed and diverse resources have to interoperate seamlessly wit...

With the advent of comparative genomics, an increasing amount of genomic data from different organisms is to be compared. This paper presents an approach to integrate bioinformatics data from various source databases using web services and a private registry. The goal is to construct an efficient framework that correctly integrates genomic databases via web services and thus allows genomic brow...

In this work, we investigate the loading and conjugation of Curcumin on oleic acid (OA) and citric acid (CA) functionalized iron oxide nanoparticles and its applications in improving contrast in MRI. Magnetic iron oxide nanoparticles (Fe3O4, MNPs) synthesized using the co-precipitation method and characterized by XRD, DLS, FT-IR, VSM and SEM. FT-IR results confirmed functionalization with oleic...