Bacterial attachment is crucial in many biotechnological applications, but important bacterial strains cannot form biofilms. Biofilms can damage materials, and current strategies to manage biofilms are focused on inhibition removal of biofilm. Biofilm formation inevitable when materials exposed microbes instead biofilm prevention, we propose management microbial composition by with beneficial m...

Introduction: S. aureus and E. coli are pathogen that can cause persistent infections due to antibiotic resistance mechanisms its ability adhere form biofilm.The search for new agents from natural resources counter microbial biofilm is an urgent priority in healthcare. Objetive: Chemical composition antibacterial anti-biofilm activity of Plectranthus amboinicus essential oil (PAEO) carvacrol we...

Acinetobacter baumannii is a prominent emerging pathogen responsible for variety of hospital-acquired infections. It can contaminate inanimate surfaces and survive in harsh environmental conditions prolonged periods time the form biofilm. Biofilm difficult to remove with only one method disinfection, so combined disinfection methods biocidal active substances are needed biofilm eradication. Add...

Abstract Background Peri-implant mucositis and peri-implantitis are biofilm-related diseases causing major concern in oral implantology, requiring complex anti-infective procedures or implant removal. Microbial biosurfactants emerged as new anti-biofilm agents for coating implantable devices preserving biocompatibility. This study aimed to assess the efficacy of rhamnolipid biosurfactant R89 (R...

Signal-mediated interactions between the human opportunistic pathogens Pseudomonas aeruginosa and Candida albicans affect virulence traits in both organisms. Phenotypic studies revealed that bacterial supernatant from four P. aeruginosa strains strongly reduced the ability of C. albicans to form biofilms on silicone. This was largely a consequence of inhibition of biofilm maturation, a phenomen...

Biofilm is a sessile bacterial accretion embedded in self-producing matrix. It is the root cause of about 80% microbial infections in human. Among them, E. coli biofilms are most prevalent in medical devices associated nosocomial infections. The objective of this study was to inhibit biofilm formation by targeting gene involved in quorum sensing, one of the main mechanisms of biofilm formation....

Fungal infections are an increasing clinical problem. Decreased treatment effectiveness is associated with biofilm formation and drug recalcitrance is thought to be biofilm specific. However, no systematic investigations have tested whether resistance mechanisms are shared between biofilm and planktonic populations. We performed multiplexed barcode sequencing (Bar-seq) screening of a pooled col...

BACKGROUND Proteus spp. bacilli belong to opportunistic human pathogens, which are primarily responsible for urinary tract and wound infections. An important virulence factor is their ability to form biofilms that greatly reduce the effectiveness of antibiotics in the site of infection. OBJECTIVES The aim of this study was to determine the value of the minimum concentration of ciprofloxacin t...

Quorum sensing (QS) is a global gene regulatory mechanism in bacteria for various traits including virulence factors. Disabling QS system with anti-infective agent is considered as a potential strategy to prevent bacterial infection. Mangifera indica L. (mango) has been shown to possess various biological activities including anti-QS. This study investigates the efficacy of leaf extracts on QS-...