BACKGROUND Screening scales for bipolar disorder including the Mood Disorder Questionnaire (MDQ) and Bipolar Spectrum Diagnostic Scale (BSDS) have been plagued by high false positive rates confounded by presence of borderline personality disorder. This study examined the accuracy of these scales for detecting bipolar disorder among patients referred for eating disorders and explored the possibi...

Bipolar Disorders affect a substantial minority of the population and result in significant personal, social and economic costs. Understanding of the causes of, and consequently the most effective interventions for, this condition is an area requiring development. Drawing upon theories of Bipolar Disorder that propose the condition to be underpinned by dysregulation of systems governing behavio...

objective: to study the prevalence and demographic characteristics of mood disorders among iranian adults. method: in this cross-sectional population-based epidemiological study (age > 18) in iran, 25180 individuals were selected through a randomized cluster sampling method for a diagnosis using the schedule for affective disorders and schizophrenia (sads). they were then interviewed at home by...

Developments in genomic and statistical technologies have dramatically advanced our understanding of the role of genes in complex traits, including psychiatric disorders. Much of the focus has been on the identification of specific variants involved in disease, with more than 12 000 genome-wide significant associations reported in the past few years. Beyond associations between genetic variants...