A recent study identified ursolic acid (UA) as a potent stimulator of muscle protein anabolism via PI3K/Akt signaling, thereby suggesting that UA can increase Akt-independent mTOR complex 1 (mTORC1) activation induced by resistance exercise via Akt signaling. The purpose of the present study was to investigate the effect of UA on resistance exercise-induced mTORC1 activation. The right gastrocn...

background : cancer is a disease which is identified by abnormal deformation of the cells. one of the common side effects of the cancer is fatigue that affects on patients’ life quality and leads to disability. exercise has an important role in improving these patients’ life quality and can be used as a complementary treatment during and after the cancer treatment. unfortunately, despite good e...

BACKGROUND The purpose of this study was to evaluate the effect of two sessions of resistance exercise with different volumes on post-exercise hypotension, forearm blood flow, and forearm vascular resistance in hypertensive elderly subjects. METHODS The study was conducted with ten hypertensive elderly (65±3 years, 28.7±3 kg/m(2)) subjected to three experimental sessions, ie, a control sessio...

the purpose of this study was to examine the effects of omega3 and aerobic exercise intervention on the calcium metabolism regulating hormones in non – athlete postmenopausal women. for this purpose 40 healthy non – athlete postmenopausal women with age 57.72±3.53 years, height 157,75±9,24 cm, weight 58.08±12.76kg, bmi 23.78±3.73kg/m2, fat 23.18±4.68% volunteered in this study. subjects in a do...

BACKGROUND Resistance training is a potent stimulus to induce muscle hypertrophy. Supplemental protein intake is known to enhance gains in muscle mass through activation of the mammalian target of rapamycin complex 1 (mTORC1) pathway, which initiates protein translation. While the optimal dose of high quality protein to promote post exercise anabolism in young or older men has been investigated...

This paper reports that the selective beta(2)-adrenergic receptor agonist clenbuterol affects bone metabolism in growing 3-mo-old male Wistar rats treated over 8 wk. Thirty-two 3-mo-old growing Wistar rats weighing 234 +/- 2 g were assigned to a progressive isometric force, strength-training exercise program plus oral clenbuterol (2 mg x kg body wt(-1) x day(-1)) for 5 days each week, exercise ...

Blood flow restriction (BFR) exercise may be an alternative form of resistance training; however, a side of effect of BFR resistance exercise is acute muscle pain. Typically, BFR exercise studies restrict blood flow with a cuff continuously during the exercise bout, including rest periods. However, others have used intermittent BFR where the cuff is inflated only during sets. We performed two s...