A 54-year-old man was admitted to the hematology department for exploration of splenomegaly. The blood count showed an isolated normochromic normocytic anemia (9.9 g/dL). Bone marrow aspiration a rich with estimated 35% plasma cell infiltration made up dystrophic cells (plasma flamed cytoplasm, centered nuclei, multinuclearity), making diagnosis multiple myeloma.

recently, the role of myostatin (mstn) in controlling insulin resistance (ir( has been known. the aim of this study was to determine acute and delayed response of mstn and ir to circuit resistance exercise. for this purpose, 12 healthy men volunteered and participated in 2 sessions of the resistance exercise and control with one-week interval. after a session to instruct how to perform resistan...

objective: multiple myeloma (mm) is a plasma cell malignancy where plasma cells are increased in the bone marrow (bm) and usually do not enter peripheral blood, but produce harmful factors creating problems in these patients (e.g. malignant plasma cells over activate osteoclasts and inhibit osteoblasts with factors like rankl and dkk). these factors are a main cause of bone lesion in mm patient...

Objective: Pili (Canarium ovatum, Engl.) pomace is an underutilized agricultural waste that possesses great potential to be regarded as a functional food ingredient. The aim of this study was to measure the polyphenol content and antioxidant activity of pili pomace drink and determine the influence of heating on these parameters. Moreover, it sought to assess the acute effects of thermally proc...

    In this double blind crossover study we assessed the bioequivalence of 200 mg enteric coated sodium valproate tablets manufactured by Roozdarou with 200 mg enteric coated sodium valproate (Orlept) manufactured by Desitin, Germany. Twelve healthy male volunteers were administered a single dose of 600 mg sodium valproate manufactured by Roozdarou, followed by a similar dose of Orlept, 2 weeks...

it has been well established that the secretions of thyroid hormones and growth hormone (gh) isunder the regulation of different neurotransmitters. the goal of this study was to determine whethersubstance-p, as a neurotransmitter, regulates the mean plasma concentrations of thyroxin (t4),triiodothyronine (t3), gh, milk amount and constituents in sanan goats. nine sanan goats were randomlydivide...

objective: because of the importance iron metabolism and role of hepcidin in running, the present study investigates the effects of one event of submaximal exercise on plasma hepcidin concentrations in male runners. methods: for this purpose, we selected eight runners who were athletic team members of mazandaran university with an average age of 21.7±1.34 years, height of 175.6±5.88 cm, weight ...

Blood plasma separation from undiluted blood is an essential step in many diagnostic procedures. This study focuses on the numerical optimization of microfluidic separator (BPS) and experimental validation results to achieve portable with high purity reasonable yield. The proposed design has two parts: a microchannel for processing tank below aforementioned main channel collection. uses 3D comp...

Background: It is well documented that fetal DNA can cross the placenta and is present in peripheral maternal blood during pregnancy in human. This fetal DNA also named circulating cell free fetal DNA, has emerged as a valuable source for genetic evaluation. Compared with humans, ovine species have a different structure of placental (synepitheliochorial) with no direct contact between the troph...