normal 0 false false false en-us x-none ar-sa background: cisplatin (cis-diamminedichloroplatinum ii; cp) is used widely as an antitumor drug in clinics, but is accompanied with renal toxicity. cisplatin induced nephrotoxicity consists of change in kidney weight, histological changes in kidney and increase in serum creatinine (cr) and blood urea nitrogen (bun). this study was designed to find o...

BACKGROUND Creatine monohydrate has become a very popular nutritional supplement for its ergogenic effects. The safety of creatine monohydrate has previously been confirmed. However with each novel form of creatine that emerges, its safety must be verified. Therefore, the purpose of this study was to examine the safety of a novel form of creatine, creatine nitrate (CN), over a 28 day period. ...

tramadol is a synthetic, centrally acting opioid analgesic that has the best analgesic efficacy without excessive sedation and significant side effects in the postoperative pain relief in dogs. objectives: in this study, hematological and biochemical changes due to short usage of tramadol were assessed in clinically healthy dogs. methods: for this purpose, eighteen male mongrel dogs aged 14 to ...

Context Urinary nitrogen excretion by grazing cattle causes environmental pollution. Selecting for cows with a lower concentration of urinary may reduce the impact. While is difficult to measure, blood urea (BUN), mid-infrared spectroscopy (MIR)-predicted BUN (MBUN), which predicted from MIR spectra measured on milk samples, and (MUN) are potential indicator traits. Australia New Zealand have i...

β-Glucan purified from oats (OG) and bitter melon, Momordica charantia Linn (MC), water extracts have shown favorable effects on diabetes and its complications. We investigated to find out the optimal composition showing hypoglycemic and antidiabetic complication effects in variable compositions (OG:MC = 1:1, 1:2, 1:4, 1:6, 1:8, 1:10, 2:1, 4:1, 6:1, 8:1, 10:1). Extracts were administered orally...

Submit Manuscript | http://medcraveonline.com Abbreviations: CA: Carnitine; T-CA: Total Carnitine; F-CA: FreeCarnitine; Ac-CA: Acyl-Carnitine; L-CA: Levo-Carnitine; LC: Liver Cirrhosis; BTR: Branched-chain amino acids to Tyrosine Ratio; OHE: Overt Hepatic Encephalopathy; MHE: Minimal Hepatic Encephalopathy; eGFR: estimated Glomerular Filtration Rate; CKD: Chronic Kidney Disease; FFA: Free Fatty...

This study aimed to evaluate the toxicity of Cladophora glomerata and Microspora floccosa ethanolic extracts in rats. Acute toxicity was tested with a single oral administration of the extract at a dose of 25 g/kg bd wt. Mortality, behavior, amount of food intake, body weight, and any abnormalities of the visceral organs, were observed. The results showed that the extract caused neither mortali...

We aimed to investigate the association between zinc (Zn) supplementation and serum levels of copeptin, high-sensitive C-reactive protein (hs-CRP), glycemic control, anthropometric parameters renal function in Zn -deficient diabetic hemodialysis patients (DHPs). This randomized, double-blind, placebo-controlled trial (RCT) was conducted on 46 DHPs with Zn-deficiency. The supplement group (n = 2...

In this study, the contrast-induced-nephropathy (CIN) of vascular patients who had undergone angiography was quantitatively evaluated using a semi-empirical model. The model compiled six essential serum readings and biological data from 70 patients in order to develop a 1st-order nonlinear equation with 16 defined terms. The expectation value of the model was used to predict the serum creatinin...

Background: Chronic kidney disease (CKD) remains a public health concern of 21st century. Each year, over million people die from CKD resulting the lack proper diagnosis and treatment this terrible urinary system. Non-communicable diseases (NCDs) cause roughly 60% all deaths worldwide. There is insufficient data in Rwanda for management other NCDs facilities. Renal substitution therapy appears ...