BACKGROUND It is uncertain whether depression and antidepressant use are associated with decreased bone mineral density (BMD) and whether these relationships differ for men and women. METHODS The study used a case-cohort design within the Baltimore Epidemiologic Catchment Area Study, a population-based sample of adults that recently completed its 23-year follow-up. Depression was measured at ...

OBJECTIVE The 12/15-lipoxygenase gene ALOX15 is reported to be a negative regulator of BMD in knockout mice. Nonetheless results are controversial as over-expression of ALOX15 protects against inflammation-related bone loss. The aim of the present study is to systematically study the relation of ALOX15 polymorphisms in BMD variation in southern Chinese women. METHODS Ten tag single nucleotide...

Objectives : By observing the effect of acupoint catgut embedding on intestinal flora ovariectomized osteoporotic rats, correlation between regulation and prevention treatment osteoporosis was discussed preliminarily. Methods Result: Compared with Group A B, bone mineral density (BMD) femur tibia in C decreased significantly (p<0.05), indicating successful modeling. C, BMD D increased (p<...

OBJECTIVE This report presents bone measurement data from dual-energy X-ray absorptiometry scans of the lumbar spine and proximal femur for persons aged 8 years and over from the National Health and Nutrition Examination Survey (NHANES) 2005-2008. METHODS Means, standard deviations, and selected percentiles were calculated for the proximal femur and lumbar spine (total and subregions) by sex,...

CONTEXT Some female athletes may have decreased bone mineral density (BMD), which puts them at higher risk for stress fractures and future osteoporosis. OBJECTIVE To compare site-specific BMD among National Collegiate Athletic Association Division I varsity female athletes and to determine predictor variables of BMD measurements. DESIGN Between-groups design. SETTING University health car...

BACKGROUND Currently, clinical trials for new therapeutic strategies are being planned for Duchenne and Becker muscular dystrophies (DMD/BMD). However, it is difficult to obtain adequate numbers of patients in clinical trials. As solutions to these problems, patient registries are an important resource worldwide, especially in rare diseases such as DMD/BMD. METHODS We developed a national reg...

UNLABELLED We performed a genome scan using BMD data of the forearm and hip on 664 individuals in 29 Mexican-American families. We obtained evidence for QTL on chromosome 4p, affecting forearm BMD overall, and on chromosomes 2p and 13q, affecting hip BMD in men. INTRODUCTION The San Antonio Family Osteoporosis Study (SAFOS) was designed to identify genes and environmental factors that influen...

OBJECTIVE The objective of this study was to evaluate the relations between bone mineral density (BMD) and lead in blood, tibia, and patella and to investigate how BMD modifies these lead biomarkers in older women. DESIGN In this study, we used cross-sectional analysis. PARTICIPANTS We studied 112 women, 50-70 years of age, including both whites and African Americans, residing in Baltimore,...

OBJECTIVE To compare bone mineral density (BMD), investigate factors associated with BMD, and examine the prevalence of low BMD in athletes and non-athletic controls. METHODS The study included a questionnaire (part I), measurement of BMD (part II), and a clinical interview (part III). All Norwegian female athletes on national teams (n = 938) and an aged matched random sample of non-athletic ...

BACKGROUND Osteoporosis is a major complication of beta thalassemia major (TM). Increased oxidative stress and its controlling genes were linked to osteoporosis. Ile105 Val variant is a functional polymorphism of Glutathione S-transferase P1 (GSTP1), with reduced anti-oxidative property. No data are available about this variant or its association with osteoporosis among thalassemia patients yet...