sebaceous carcinoma is a relatively rare cutaneous tumor that is most commonly derived from the sebaceous glands located in periorbital area. the extraocular occurrence of this tumor is very rare. we report a case of an 85 years old woman who presented with a slowly enlarging mass on the right temporal region. histological examination of the lesion revealed a malignant sebaceous carcinoma occur...

Lesion to symptom mapping (LSM) is a crucial tool for understanding the causality of brain-behavior relationships. The analyses are typically performed by applying statistical methods on individual brain voxels (VLSM), a method called the mass-univariate approach. Several authors have shown that VLSM suffers from limitations that may decrease the accuracy and reliability of the findings, and ha...

Understanding the intensity characteristics of brain lesions is key for defining image-based biomarkers in neurological studies and predicting disease burden outcome. In this work, we present a novel foreground-based generative method modelling local lesion that can both generate synthetic on healthy images synthesize subject-specific pseudo-healthy from pathological images. Furthermore, propos...

It is rare for low-grade gliomas to disseminate to the leptomeninges. However, low-grade gliomas with dissemination to the leptomeninges have been occasionally reported in children, and have generally been associated with local recurrence. A 16-year-old boy sought evaluation for diplopia and gait disturbance. A brain magnetic resonance imaging (MRI) revealed pontine mass, which was proved to be...

This article presents methods and results of surgical treatment and radiation therapy of brain metastases in breast cancer patients (brain metastases from breast cancer BMF-BC). Based on the literature data, it was shown that patients with single BMF-BC, aged less than 65 years, with Karnofsky score (KPS) of 70 or more and with cured or controlled extracranial disease are the best candidates to...

background: alzheimer’s disease was known as a progressive neurodegenerative disorder in the elderly and is characterized by dementia and severe neuronal loss in the some regions of brain such as nucleus basalis magnocellularis. it plays an important role in the brain functions such as learning and memory. loss of cholinergic neurons of nucleus basalis magnocellularis by ibotenic acid can commo...

Plasmacytoma of the calvarium is very rare, accounting for the 0.7 % of all plasmacytomas [1–5]. The most common locations are the thoracic and lumbar spine (30–40 % of cases). Involvement of the hip, femurs, and ribs is less frequent [6]. Plasmacytoma of the calvarium can be indistinguishable from other lytic lesions, especially metastatic disease. Meningioma, eosinophilic granuloma, and dermo...