Venous thromboembolism is a known complication of cancer which impacts on patient mortality and quality of life. The primary site of cancer is an important risk factor, with highest rates observed in patients with brain, pancreas, gastric, kidney, ovary and lung cancers. The extent of metastatic spread further adds to the risk. In this article, we present the case of a young patient who was dia...

The Eker rat is a model for human tuberous sclerosis (TSC) caused by a mutation in the Tsc2 gene. We describe here histological and immunohistochemical findings of the brain lesions in Eker rats, with emphasis on 2 novel lesions found in this study: a cortical tuber and an anaplastic ganglioglioma. The rat cortical tuber resembled those of humans, and further confirmed the value of this animal ...

We report a case of a 10-year-old girl with a tumour of the right temporoparietal region of the brain. The tumour consisted of three morphologically distinct portions: a well-differentiated one containing a mixture of a ganglioglioma with adipocytic-like cells and focal chondroid metaplasia, a separate island with neurocytic differentiation, and the malignant one, which exhibited an organoid pa...

BACKGROUND The co-occurrence of intracranial arteriovenous malformations (AVMs) and cerebral neoplasms is exceedingly rare but may harbor implications pertaining to the molecular medicine of brain cancer pathogenesis. CASE DESCRIPTION Here, we present a case of de novo AVM within an isocitrate dehydrogenase 1 mutated anaplastic oligodendroglioma (WHO Grade III) and review the potential contri...

Harlequin syndrome is a rare neurological condition that results in unilateral facial flushing and sweating. Although the syndrome is generally a benign condition with complete resolution if appropriate treatment is initiated, unilateral facial flushing can be a sign of several serious conditions and should be thoroughly investigated. Sudden onset of facial flushing related to harlequin syndrom...

while ovarian masses are common findings in gynecology, unusually huge masses are quite rare. however, such cases can still be found today. mismanagement of common complaints in patients can be a leading cause of facing such findings. herein, we introduce a case of a giant ovarian cyst, which was mismanaged in a young virgin female patient. the patient had received gastrointestinal medications ...

abstract gastric cancer is one of the most common and most fatal neoplasms in human. its skeletal metastasis is less frequent, particularly when solitary. the objective of this article is to represent a case of solitary fibular metastasis from this cancer not reported before based on medline search.

objectives we undertook this study to compare the results of hormone receptor assessment in cnb and surgical samples on our patients. patients and methods hormone receptor status was determined in cnb and surgical samples in breast cancer patients whose cnb and operation had been performed in this institute from 2009 to 2011 and had not undergone neoadjuvant chemotherapy. results about 350 pati...

background: information regarding solid pseudopapillary neoplasm (spn) of the pancreas is limited in iran. we aimed to review the clinicocytopathological features and follow-up of patients with spn of pancreas who were diagnosed in a single center in iran. methods: seven patients with spn of the pancreas were diagnosed during january 2010 to march 2015 at the digestive disease research institut...

Malignant brain tumors are the leading cause of cancer death among pediatric patients, and medulloblastoma constitutes 20% of them. Currently, the treatment is risk-adapted. Maximum surgical resection is recommended, always followed by chemotherapy and neuroaxis radiotherapy. In spite of the improving survival rate, survivors succumb to treatment-induced side effects. To reduce toxic effects, m...