PURPOSE Very few tumor molecular markers have been identified that are highly specific for breast cancer cells when applied to blood and bone marrow (BM). Stanniocalcin (STC)-1 is a recently discovered human gene that has been implicated in cellular calcium homeostasis and resistance to hypoxia and is located on chromosome 8p in a region associated with amplification in breast cancer. We invest...

Breast cancer is one of the most common types of cancer in women. Screening mammography is a low‑dose X‑ray examination of breasts, which is conducted to detect breast cancer at early stages when the cancerous tumor is too small to be felt as a lump. Screening mammography is conducted for women with no symptoms of breast cancer, for early detection of cancer when the cancer is most treatable an...

background: physical examination (pe) and breast mri are two of the current methods which have usually used in diagnosis of primary breast cancer. their accuracy in detection of: either complete response or presence of residual tumor, however, has not yet been established in patients who have been received neoadjuvant chemotherapy (nac). the purpose of this study was to evaluate the diagnostic ...

Breast cancer is one of the major causes of death among women. Small clusters of micro calcifications appearing as collection of white spots on mammograms show an early warning of breast cancer. Early detection performed on X-ray mammography is the key to improve breast cancer diagnosis. In order to increase radiologist’s diagnostic performance, several computer-aided diagnosis (CAD) schemes ha...

Guidelines for the early detection of breast cancer vary across agencies. This article compares available breast cancer screening guidelines for women of average or increased risk, as well as for older women. Nurses are challenged to explain risk factors, discuss variations in guidelines, and assist women in understanding the strengths and limitations of various screening modalities for the ear...

Breast cancer is most frequently occurring disease among women. Early detection is a reliable method which can prevent breast cancer spreading to distant organs. Mammography is considered as the most reliable method for early detection. The purpose of this paper is to succinctly review recent progress and current state of art knowledge related to detection of architectural distortion in mammogr...

Hypermethylated genes are emerging as some of the most promising, practical and powerful biomarkers for breast cancer detection and perhaps even of risk assessment. We have assembled a panel of methylated gene detection markers and tested them by Quantitative Multiplex Methylation-Specific PCR (QM-MSP) in breast cancer. Here we two pilot studies: 1) detection of cancer in DNA from spontaneous n...

Human mammaglobin is a member of the uteroglobin proteins family that has recently been tested as a specific marker for breast cancer. While low levels may be seen in normal breast tissue, expression is increased dramatically in breast cancer and is correlated with higher grade. Detection in blood and body fluids is also correlated with cancer metastasis, and its levels with prognosis. This pro...

Breast cancer is leading cause of death among female cancer patient. However the early detection of breast cancer is dependent on both radiologist’s ability to read mammograms and the quality of mammograms images. Mammography is the effective technique for the screening of breast cancer and abnormalities detection. Screening is one of the key factor to reduce the death rates. The strong correla...