Understanding how the variability of protein structure arises during evolution and leads to new structure-function relationships ultimately promoting evolutionary novelties is a major goal of molecular evolution and is critical for interpreting genome sequences. We addressed this issue using the ecdysone receptor (ECR), a major developmental factor that controls development and reproduction of ...

Classification is an essential process in science. The creation (and refinement) of taxonomies is basic to many scientific tasks. Activities such as theory formation, law induction, and experimentation undoubtedly rely upon a sound classification of elements, e.g., physical, chemical, biological. More specifically, taxonomic revision can play an important role in scientific discovery. The detec...

There are two possible answers: the universe and life and its diversity—natural phenomena—are the product of 1) a combination of only natural laws and chance (the “naturalistic hypothesis)”; or 2) a combination of law, chance, and design—the activity of a mind or some form of intelligence that has the power to manipulate matter and energy (the “design hypothesis”). The latter produces purpose, ...

Martin Brecht: Luther. - Stuttgart: Calwer Verl. 2. Bd.: Ordnung und Abgrenzung der Reformation 1521-1532. 1986. 517 S.: Ill.3. Die Erhaltung Kirche 1532-1546. 1987. 471 Ill.

Although the forces behind the evolution of imperfect mimicry remain poorly studied, recent hypotheses suggest that relaxed selection on small-bodied individuals leads to imperfect mimicry. While evolutionary history undoubtedly affects the development of imperfect mimicry, ecological community context has largely been ignored and may be an important driver of imperfect mimicry. Here we investi...

The increasing interest in archiving all of humankind’s cultural artifacts has resulted in the digitization of millions of books, and soon a significant fraction of the world’s books will be online. Most of the data in historical manuscripts is text, but there is also a significant fraction devoted to images. This fact has driven much of the recent increase in interest in query-by-content syste...

In patients with ALS, conventional MR imaging is frequently noninformative, and its use has been restricted to excluding other conditions that can mimic ALS. Conversely, the extensive application of modern MR imaging-based techniques to the study of ALS has undoubtedly improved our understanding of disease pathophysiology and is likely to have a role in the identification of potential biomarker...

El presente artículo analiza la cuestión del materialismo y su relación con el arte en pensamiento de Walter Benjamin. Es una harto controvertida los debates sobre Benjamin, estudia minuciosamente sus dos textos fundamentales que abordan cuestión: autor como productor La obra era reproductibilidad técnica. Antes ello, se enmarca problema contexto época y, especial, Benjamin Brecht, fue tomado u...