This paper describes a Bayesian framework for performing relational graph matching by discrete relaxation. Our basic aim is to draw on this framework to provide a comparative evaluation of a number of contrasting approaches to relational matching. Broadly speaking there are two main aspects to this study. Firstly we focus on the issue of how relational inexactness may be quantified. We illustra...

Do remembering and knowing differ qualitatively (reflecting distinct underlying processes) or quantitatively (reflecting different levels of strength)? Broadly speaking, models of remember-know judgments based on these alternatives have been tested by examining the proportion of remember and know responses that are made across conditions or levels of confidence. Here, we consider reaction time ...

Broadly speaking, algebraic topology consists of associating algebraic structures to topological spaces that give information about their structure. An elementary, but fundamental, example is provided by the theory of covering spaces, which associate groups to covering spaces in such a way that the universal cover corresponds to the fundamental group of the space. One natural question to ask is...

Broadly speaking, pharmaceutical policy in Spain has been unable to control either the price or the volume of drugs prescribed. Limited attempts have been made to bring together the regulation of the pharmaceutical market and policies, in pursuit of the desired goals of efficiency and quality. This paper assesses the regulation of the Spanish pharmaceutical market over the last two decades by e...

There is an ongoing debate over the evidentiary standards that should be applied for introduction of new diagnostics into routine clinical practice. Many call for evidence of "clinical utility," i.e., a positive impact on patient outcomes. A diagnostic, when used with a medicine, has clinical utility if it improves the outcomes of drug therapy. Improved outcomes may be defined broadly, includin...

We develop in this paper a theoretical framework for the topological study of time series data. Broadly speaking, we describe geometrical and topological properties of sliding window embeddings, as seen through the lens of persistent homology. In particular, we show that maximum persistence at the point-cloud level can be used to quantify periodicity at the signal level, prove structural and co...

Broadly speaking, patients that have difficulty ventilating and/or difficulty oxygenating could benefit from mechanical ventilation. Hypoventilation for the purposes of this article is defined as partial pressure of carbon dioxide (PaCO2) in arterial blood that is greater than 60 mmHg. Oxygenation difficulties may exist when the partial pressure of oxygen (PaO2) in arterial blood falls below 60...

We describe results from the third stage of a project to build a statistical model for hurricane tracks. In the first stage we modelled the unconditional mean track. In the second stage we modelled the unconditional variance of fluctuations around the mean. Now we address the question of how to model the autocorrelations in the standardised fluctuations. We perform a thorough diagnostic analysi...

in the healthcare context, whistleblowing has come to the fore of political, professional and public attention in the wake of major service scandals and mounting evidence of the routine threats to safety that patients face in their care. this paper offers a commentary and wider contextualisation of mannion and davies, ‘cultures of silence and cultures of voice: the role of whistleblowing in hea...

conclusions the findings of this study indicate that older children are more proficient in comprehension of color words compared to younger children, and girls are more proficient than boys. the two easiest and two most difficult color words for children to comprehend within the 3 age groups were “black” and “red” and “phosphoric-green” and “turquoise-blue,” respectively. there was a positive r...