نتایج جستجو برای: bsa

تعداد نتایج: 6231  

Dietary flavonoids show beneficial effects in the prevention of chronic diseases. However, flavonoid bioavailability is poor, probably due to their interaction with serum albumins. In the current work, the binding interactions of eight related flavonoids, sharing a similar core structure, with bovine serum albumin (BSA) were investigated by fluorescence spectroscopy. The binding affinities of t...

2017
Maryam Sharifi Jafar Ezzati Nazhad Dolatabadi Farzaneh Fathi Mostafa Zakariazadeh Abolfazl Barzegar Mohammad Rashidi Habib Tajalli Mohammad-Reza Rashidi

Introduction: The interactions between biomacromolecules such as serum albumin (SA) and various drugs have attracted increasing research attention in recent years. However, the study of SA with those drugs that have relatively high hydrophilicity and a lower affinity for SA could be a challenging issue. At the present study, the interaction of bovine SA (BSA) with neomycin as a hydrophilic drug...

2017
Henrique Morais Jessica Neves Hugo Maciel Ribeiro Marta Ferreira Narcisa Guimarães Nuno Azenha Raquel Dias Alice Fonseca Lucilia Conceição

OBJECTIVES Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) model as prognostic tools. MATERIALS AND METHODS Retrospective study involving all patients with Four...

2004
B. P. Kamat

The mechanism of interaction of cyanocobalamin (CB) with bovine serum albumin (BSA) has been investigated by spectrofluorometric and circular dichroism methods. Association constant for the CB-BSA system showed that the interaction is non-covalent in nature. Binding studies in the presence of an hydrophobic probe, 8-anilino-1naphthalene sulphonic acid, sodium salt (ANS) showed that there is hyd...

Journal: :International journal of pharmaceutics 2000
B Baras M A Benoit J Gillard

Microparticles were produced by spray-drying from a high molecular weight polylactide (PLA R207) for the development of long-lasting controlled release systems of vaccines, which may be designed to obviate the need for booster doses. The current investigation considered the effect of both technological parameters (inlet air temperature and spray rate of feed) and polymeric solutions (polymer co...

Journal: :Biotechnology and bioengineering 2006
Bin Yang Charles E Wyman

Cellulase and bovine serum albumin (BSA) were added to Avicel cellulose and solids containing 56% cellulose and 28% lignin from dilute sulfuric acid pretreatment of corn stover. Little BSA was adsorbed on Avicel cellulose, while pretreated corn stover solids adsorbed considerable amounts of this protein. On the other hand, cellulase was highly adsorbed on both substrates. Adding a 1% concentrat...

Journal: :Dalton transactions 2012
Chenguang Li Lei Xing Shunai Che

Zn-loaded bovine serum albumin nanoparticles (Zn-BSA nanoparticles) were prepared and used as carriers for pH-responsive anticancer drug delivery. Zinc was introduced into this system to increase the stability of the BSA nanoparticles and to load the anticancer drug based on the coordination bonding formation of Zn-BSA and Zn-drug molecules, respectively. The cleavage of either the "Zn-BSA" or ...

Journal: :Blood 2007
Toshimitsu Irei Hideki Ohdan Wendy Zhou Kohei Ishiyama Yuka Tanaka Kentaro Ide Toshimasa Asahara

We demonstrated a novel strategy for specific and persistent inhibition of antibody (Ab) production against blood group A or B carbohydrate determinants necessary for successful ABO-incompatible transplantation. Similar to human blood group O or B individuals, mice have naturally occurring Abs against human blood group A carbohydrates in their sera. B cells with receptors for A carbohydrates in...

2007
G. M. Lindner J. F. Dickey J. R. Hill

The objectives of this s tudy were to test the effects of four levels of bovine serum albumin (BSA) on the development of ovine embryos cultured in Brinster's and Whitten's media and to examine the extent of in vitro development of ovine embryos cultured from various cell stages. Two hundred and forty-three oneto 16-celi ovine embryos were cultured in Brinster's medium (BMOC-2 plus .1% w/v dext...

2017
Yousef Sohrabi Vahid Panahi-Azar Abolfazl Barzegar Jafar Ezzati Nazhad Dolatabadi Parvin Dehghan

Introduction: Ascorbyl palmitate (AP) is an example of natural secondary food antioxidant, which has been used for oxidative rancidity prevention in food industry. In this study, the interaction of AP with bovine serum albumin (BSA) was investigated. Methods: The mechanism of BSA interaction with AP was investigated using spectroscopic methods (UV-Vis, fluorescence). The thermodynamic parameter...

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