Circulating blood volume (CBV) was prospectively measured in patients with almost solely smoke inhalation injury (Group I: 10 patients) and in patients with severe cutaneous burn (Group B: 6 patients) consecutively until 96 hours after injury, to assess the effect of either injury on intravascular volume status by the pulse dye-densitometry method. All participants were treated by an ordinary f...

Reconstruction of the neck following a burn injury poses a significant challenge to reconstructive burn surgeons. Here, we report a case of successful application of pre-expanded occipito-dorsal flaps in the reconstruction of postburn scars and contractures in the neck. The patient was a 10-year-old boy who sustained scars and contractures secondary to a burn injury 4 years ago. "Super-thin" fl...

The burn injury can one of the most serious and devastating injuries among people of all ages. The aim of the study was to identify correlates of physical and psychosocial functioning among burn patients. The study was conducted at the burn units of El-Mansoura University Hospital. Design: descriptive correlational design was used. Tools which were used for data collection: 1) Sociodemographic ...

Background: Thermal injury can cause many changes in the skin-local responseand in the body in general –systemic response; the metabolic changes represent an important one among systemic response. Dyslipidemia after burn injury is one of the important alterations that resulted from many factors like hypermetabolic state in burn, release of hormones and inflammatory mediators, the aim of this st...

Severe burn injury produces a plethora of metabolic abnormalities which contribute to the prolonged morbidity of burn survivors. The authors have recently demonstrated trans-differentiation of white adipose tissue (WAT) after burn trauma, toward a more thermogenic phenotype. However, the impact of burn injury on subcutaneous WAT (sWAT) morphology in humans is unknown. Here, the authors studied ...

Chemical burns are a major cause of corneal injury. Oxidative stress, inflammatory responses and neovascularization after the chemical burn aggravate corneal damage, and lead to loss of vision. Although NADPH oxidases (Noxs) play a crucial role in the production of reactive oxygen species (ROS), the role of Noxs in chemical burn-induced corneal injury remains to be elucidated. In the present st...

BACKGROUND Survivors of physical and emotional trauma experience enduring occupational, psychological and quality of life impairments. Examining survivors from a large fire provides a unique opportunity to distinguish the impact of physical and emotional trauma on long-term outcomes. The objective is to detail the multi-dimensional long-term effects of a large fire on its survivor population an...

OBJECTIVE To investigate if adults who are hospitalised for a burn injury have increased long-term hospital use for musculoskeletal diseases. DESIGN A population-based retrospective cohort study using linked administrative health data from the Western Australian Data Linkage System. SUBJECTS Records of 17,753 persons aged at least 20 years when hospitalised for a first burn injury in Wester...

Severe injury induces a temporal shift in immune reactivity that can cause serious complications or even death. We previously reported that mice exposed to bacterial superantigen (SAg) early after injury undergo a strong SAg response with lethal consequences. This study compares the early and late effects of burn injury on SAg reactivity in vivo to establish how injury influences adaptive immun...

purpose: to evaluate the prevalence of acute ocular chemical injuries in patients referred to labbafinejad medical center (lmc) over a period of one year. methods: all patients with chemical burns referred to lmc emergency ophthalmology service were included in the study. demographic characteristics and information regarding the burn were obtained. visual acuity assessment and slit lamp examina...