In an earlier paper from this laboratory (1) there were described the characteristics of competitive inhibition resulting from the interference of certain aromatic compounds with the association of flavin adenine dinucleotide and the separated protein of n-amino acid oxidase. Included among the inhibitors were auramine, quinine, and various other quinolines and anilines. We now present our find...

YM-47522 (1) was isolated from the fermentation broth of Bacillus sp. YL-03709B as an antifungal antibiotic. The structure of 1 was elucidated by spectroscopic analyses. YM-47522 (1) consisted of C13 carboxylic acid amide and cinnamate moieties. The relative stereochemistry was also proposed on the basis of chemical transformation into a 1,3-diol acetonide and its NMR data.

A vibration-rotation-tunneling (VRT) spectrum of (H2O)4 has been recorded near 2.04 THz (67.9 cm-1). The band origin of this ∆K ) 0 symmetric rotor spectrum is shifted by 0.1 cm-1 to the blue of that of a (D2O)4 band reported previously [Science, 1996, 271, 59]. Similar to that spectrum, each transition in the (H2O)4 spectrum exhibits a regular doublet splitting. The (D2O)4 and (H2O)4 doublet s...

We present maps at high spatial and spectral resolution in emission lines of CCH, c-C3H2, C4H, CO and CO of the edge of the Horsehead nebula obtained with the Plateau de Bure Interferometer (PdBI). The edge of the Horsehead nebula is a one-dimensional Photo–Dissociation Region (PDR) viewed almost edge-on. All hydrocarbons are detected at high signal–to–noise ratio in the PDR where intense emiss...

one-pot, four-component procedure for the synthesis of a small library of new chiral spiro- oxindolopyrrolidines with high regio-, diastereo- (>99:1 dr), and enantioselectivity (up to 80% ee) is described. in this process, the regio- and stereochemical 1,3-dipolar cycloaddition of azomethine ylides, which were generated insitu by the reaction of isatin derivatives and sarcosin,with optically ac...

This study demonstrates the potential of different cinnamate esters, namely methyl trans-cinnamate (MC), isobutyl (IBC), allyl (AC), and ethyl (EC), as environmentally friendly plasticizers for polylactide (PLA). Plasticized PLA formulations with a constant nominal wt% 20 each plasticizer are compounded in twin-screw co-rotating extruder subsequently processed by injection molding. The results ...

Morphology manipulation opens up a new avenue for controlling and tailoring the functional properties of graphene, enabling the exploration of graphene-based nanomaterials. Through mixing single-side-hydrogenated graphene (C4H) with fluorinated graphene (C4F) on one single sheet, the C4H/C4F-type graphene superlattices can self-scroll at room temperature. We demonstrate using molecular dynamic ...

We utilized the crossed molecular beams method to synthesize the butadiynyl radical, C4H(X ∑ +), via the reaction of dicarbon molecules with acetylene, under single collision conditions. Time-of-flight spectra of the radical were recorded at the center-of-mass angle (31◦) of the parent ion (m/z= 49; C4H) and of the fragments at m/z= 48 (C4), m/z= 37 (C3H), and m/z= 36 (C3) This yields relative ...